| http://purl.uniprot.org/citations/14675532 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14675532 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14675532 | http://www.w3.org/2000/01/rdf-schema#comment | "Plants use ethylene gas as a signal to regulate myriad developmental processes and stress responses. The Arabidopsis EIN3 protein is a key transcription factor mediating ethylene-regulated gene expression and morphological responses. Here, we report that EIN3 protein levels rapidly increase in response to ethylene and this response requires several ethylene-signaling pathway components including the ethylene receptors (ETR1 and EIN4), CTR1, EIN2, EIN5, and EIN6. In the absence of ethylene, EIN3 is quickly degraded through a ubiquitin/proteasome pathway mediated by two F box proteins, EBF1 and EBF2. Plants containing mutations in either gene show enhanced ethylene response by stabilizing EIN3, whereas efb1 efb2 double mutants show constitutive ethylene phenotypes. Plants overexpressing either F box gene display ethylene insensitivity and destabilization of EIN3 protein. These results reveal that a ubiquitin/proteasome pathway negatively regulates ethylene responses by targeting EIN3 for degradation, and pinpoint EIN3 regulation as the key step in the response to ethylene."xsd:string |
| http://purl.uniprot.org/citations/14675532 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(03)00969-3"xsd:string |
| http://purl.uniprot.org/citations/14675532 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(03)00969-3"xsd:string |
| http://purl.uniprot.org/citations/14675532 | http://purl.uniprot.org/core/author | "Ecker J.R."xsd:string |
| http://purl.uniprot.org/citations/14675532 | http://purl.uniprot.org/core/author | "Ecker J.R."xsd:string |
| http://purl.uniprot.org/citations/14675532 | http://purl.uniprot.org/core/author | "Guo H."xsd:string |
| http://purl.uniprot.org/citations/14675532 | http://purl.uniprot.org/core/author | "Guo H."xsd:string |
| http://purl.uniprot.org/citations/14675532 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/14675532 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/14675532 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/14675532 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/14675532 | http://purl.uniprot.org/core/pages | "667-677"xsd:string |
| http://purl.uniprot.org/citations/14675532 | http://purl.uniprot.org/core/pages | "667-677"xsd:string |
| http://purl.uniprot.org/citations/14675532 | http://purl.uniprot.org/core/title | "Plant responses to ethylene gas are mediated by SCF(EBF1/EBF2)-dependent proteolysis of EIN3 transcription factor."xsd:string |
| http://purl.uniprot.org/citations/14675532 | http://purl.uniprot.org/core/title | "Plant responses to ethylene gas are mediated by SCF(EBF1/EBF2)-dependent proteolysis of EIN3 transcription factor."xsd:string |
| http://purl.uniprot.org/citations/14675532 | http://purl.uniprot.org/core/volume | "115"xsd:string |
| http://purl.uniprot.org/citations/14675532 | http://purl.uniprot.org/core/volume | "115"xsd:string |
| http://purl.uniprot.org/citations/14675532 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/14675532 |
| http://purl.uniprot.org/citations/14675532 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/14675532 |
| http://purl.uniprot.org/citations/14675532 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/14675532 |
| http://purl.uniprot.org/citations/14675532 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/14675532 |
| http://purl.uniprot.org/uniprot/Q39255 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/14675532 |
| http://purl.uniprot.org/uniprot/Q9SKK0#attribution-1414AC3A07B2F6765E209EAD118ECBD0 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/14675532 |