| http://purl.uniprot.org/citations/14697212 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14697212 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14697212 | http://www.w3.org/2000/01/rdf-schema#comment | "WASP family proteins are involved in cortical actin cytoskeleton reorganization. Neural Wiskott-Aldrich syndrome protein (N-WASP), a ubiquitously expressed WASP homologous protein, directly binds with Cdc42, activating Arp2/3 complex. In this study, we show that N-WASP-dependent microspike formation is inhibited by formin binding protein 11 (FBP11). Endogenous FBP11 localizes with nuclear-speckles, and co-localization of N-WASP and FBP11 was observed when they were co-expressed. Epidermal growth factor (EGF) induced actin-microspike formation in COS7 cells. However, transient expression of FBP11 suppressed N-WASP-dependent actin-microspike formation by trapping N-WASP in the nucleus. These results indicate that FBP11 regulates localization of N-WASP, thus negatively regulating the function of N-WASP in the cytoplasm."xsd:string |
| http://purl.uniprot.org/citations/14697212 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2003.11.139"xsd:string |
| http://purl.uniprot.org/citations/14697212 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2003.11.139"xsd:string |
| http://purl.uniprot.org/citations/14697212 | http://purl.uniprot.org/core/author | "Suetsugu S."xsd:string |
| http://purl.uniprot.org/citations/14697212 | http://purl.uniprot.org/core/author | "Suetsugu S."xsd:string |
| http://purl.uniprot.org/citations/14697212 | http://purl.uniprot.org/core/author | "Takenawa T."xsd:string |
| http://purl.uniprot.org/citations/14697212 | http://purl.uniprot.org/core/author | "Takenawa T."xsd:string |
| http://purl.uniprot.org/citations/14697212 | http://purl.uniprot.org/core/author | "Mizutani K."xsd:string |
| http://purl.uniprot.org/citations/14697212 | http://purl.uniprot.org/core/author | "Mizutani K."xsd:string |
| http://purl.uniprot.org/citations/14697212 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/14697212 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/14697212 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/14697212 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/14697212 | http://purl.uniprot.org/core/pages | "468-474"xsd:string |
| http://purl.uniprot.org/citations/14697212 | http://purl.uniprot.org/core/pages | "468-474"xsd:string |
| http://purl.uniprot.org/citations/14697212 | http://purl.uniprot.org/core/title | "FBP11 regulates nuclear localization of N-WASP and inhibits N-WASP-dependent microspike formation."xsd:string |
| http://purl.uniprot.org/citations/14697212 | http://purl.uniprot.org/core/title | "FBP11 regulates nuclear localization of N-WASP and inhibits N-WASP-dependent microspike formation."xsd:string |
| http://purl.uniprot.org/citations/14697212 | http://purl.uniprot.org/core/volume | "313"xsd:string |
| http://purl.uniprot.org/citations/14697212 | http://purl.uniprot.org/core/volume | "313"xsd:string |
| http://purl.uniprot.org/citations/14697212 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/14697212 |
| http://purl.uniprot.org/citations/14697212 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/14697212 |
| http://purl.uniprot.org/citations/14697212 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/14697212 |
| http://purl.uniprot.org/citations/14697212 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/14697212 |