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http://purl.uniprot.org/citations/15181474http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15181474http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/15181474http://www.w3.org/2000/01/rdf-schema#comment"Retinoic acid-inducible gene-I (RIG-I) is a member of the DExH box family proteins, which have diverse roles in regulation of gene expression and cellular functions. We found RIG-I mRNA and protein were expressed in MCF-7 human breast cancer cells stimulated with interferon-gamma (IFN-gamma). This effect of IFN-gamma was observed in concentration- and time-dependent manners, and IFN-gamma also induced promoter activity of RIG-I. Transfection of GFP-RIG-I cDNA into MCF-7 cells resulted in the expression of RIG-I protein in cytoplasm. Overexpression of RIG-I induced the upregulation of IFN-gamma stimulated gene 15, which has the potential to amplify the immunomodulatory effects. We conclude that IFN-gamma induces the expression of RIG-I, which may play a role in the immunological effects of IFN-gamma."xsd:string
http://purl.uniprot.org/citations/15181474http://purl.org/dc/terms/identifier"doi:10.1139/o04-041"xsd:string
http://purl.uniprot.org/citations/15181474http://purl.org/dc/terms/identifier"doi:10.1139/o04-041"xsd:string
http://purl.uniprot.org/citations/15181474http://purl.uniprot.org/core/author"Satoh K."xsd:string
http://purl.uniprot.org/citations/15181474http://purl.uniprot.org/core/author"Satoh K."xsd:string
http://purl.uniprot.org/citations/15181474http://purl.uniprot.org/core/author"Yoshida H."xsd:string
http://purl.uniprot.org/citations/15181474http://purl.uniprot.org/core/author"Yoshida H."xsd:string
http://purl.uniprot.org/citations/15181474http://purl.uniprot.org/core/author"Imaizumi T."xsd:string
http://purl.uniprot.org/citations/15181474http://purl.uniprot.org/core/author"Imaizumi T."xsd:string
http://purl.uniprot.org/citations/15181474http://purl.uniprot.org/core/author"Borden E.C."xsd:string
http://purl.uniprot.org/citations/15181474http://purl.uniprot.org/core/author"Borden E.C."xsd:string
http://purl.uniprot.org/citations/15181474http://purl.uniprot.org/core/author"Cui X.-F."xsd:string
http://purl.uniprot.org/citations/15181474http://purl.uniprot.org/core/author"Cui X.-F."xsd:string
http://purl.uniprot.org/citations/15181474http://purl.uniprot.org/core/date"2004"xsd:gYear
http://purl.uniprot.org/citations/15181474http://purl.uniprot.org/core/date"2004"xsd:gYear
http://purl.uniprot.org/citations/15181474http://purl.uniprot.org/core/name"Biochem. Cell Biol."xsd:string
http://purl.uniprot.org/citations/15181474http://purl.uniprot.org/core/name"Biochem. Cell Biol."xsd:string
http://purl.uniprot.org/citations/15181474http://purl.uniprot.org/core/pages"401-405"xsd:string
http://purl.uniprot.org/citations/15181474http://purl.uniprot.org/core/pages"401-405"xsd:string
http://purl.uniprot.org/citations/15181474http://purl.uniprot.org/core/title"Retinoic acid-inducible gene-I is induced by interferon-gamma and regulates the expression of interferon-gamma stimulated gene 15 in MCF-7 cells."xsd:string
http://purl.uniprot.org/citations/15181474http://purl.uniprot.org/core/title"Retinoic acid-inducible gene-I is induced by interferon-gamma and regulates the expression of interferon-gamma stimulated gene 15 in MCF-7 cells."xsd:string
http://purl.uniprot.org/citations/15181474http://purl.uniprot.org/core/volume"82"xsd:string
http://purl.uniprot.org/citations/15181474http://purl.uniprot.org/core/volume"82"xsd:string