| http://purl.uniprot.org/citations/15240705 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15240705 | http://www.w3.org/2000/01/rdf-schema#comment | "We have identified two intronic regions of mouse prdm1, the gene encoding B lymphocyte-induced maturation protein-1 (Blimp-1), which confer transcriptional repression in response to Bcl-6. The Bcl-6 response element in intron 5, which is conserved between mice and humans, was studied in detail. It binds Bcl-6 in vitro and was shown by chromatin immunoprecipitation to be occupied by Bcl-6 in vivo. Neither Bcl-6 response element functions as a STAT3-response element, showing that STAT3 does not compete with Bcl-6 at these sites. Bcl-6(-/-) mice confirm the biological importance of Bcl-6-dependent repression of prdm1. These mice have elevated Ab response, increased Ig-secreting cells, and increased Blimp-1(+) cells in spleen following immunization and their splenic B cells show accelerated plasmacytic development in vitro."xsd:string |
| http://purl.uniprot.org/citations/15240705 | http://purl.org/dc/terms/identifier | "doi:10.4049/jimmunol.173.2.1158"xsd:string |
| http://purl.uniprot.org/citations/15240705 | http://purl.uniprot.org/core/author | "Yu X."xsd:string |
| http://purl.uniprot.org/citations/15240705 | http://purl.uniprot.org/core/author | "Staudt L.M."xsd:string |
| http://purl.uniprot.org/citations/15240705 | http://purl.uniprot.org/core/author | "Shaffer A.L."xsd:string |
| http://purl.uniprot.org/citations/15240705 | http://purl.uniprot.org/core/author | "Calame K.L."xsd:string |
| http://purl.uniprot.org/citations/15240705 | http://purl.uniprot.org/core/author | "Tunyaplin C."xsd:string |
| http://purl.uniprot.org/citations/15240705 | http://purl.uniprot.org/core/author | "Angelin-Duclos C.D."xsd:string |
| http://purl.uniprot.org/citations/15240705 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15240705 | http://purl.uniprot.org/core/name | "J Immunol"xsd:string |
| http://purl.uniprot.org/citations/15240705 | http://purl.uniprot.org/core/pages | "1158-1165"xsd:string |
| http://purl.uniprot.org/citations/15240705 | http://purl.uniprot.org/core/title | "Direct repression of prdm1 by Bcl-6 inhibits plasmacytic differentiation."xsd:string |
| http://purl.uniprot.org/citations/15240705 | http://purl.uniprot.org/core/volume | "173"xsd:string |
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| http://purl.uniprot.org/citations/15240705 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15240705 |
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