| http://purl.uniprot.org/citations/15304100 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15304100 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15304100 | http://www.w3.org/2000/01/rdf-schema#comment | "Expression of melanoma differentiation associated gene-7 (mda-7) also known as interleukin 24 (IL-24) decreases during melanoma cell differentiation and induces apoptosis in melanoma cells but not in melanocytes. Here we identify a novel splice variant of the cancer growth suppressor gene mda-7/IL-24 (mda-7s) that is differentially expressed in RNA preparations from normal human melanocytes, transformed melanocytes, nevi, subcutaneous metastasis, lymph node metastasis, and melanoma cell lines. The 450 bp mda-7s mRNA encodes a protein of 63 residues with a molecular weight of 12 kDa. mda-7s lacks exons 3 and 5 of the full-length transcript and contains only 14 amino acids of homology to MDA-7 located within the signal peptide region of the wild-type sequence. Despite minimal homology, MDA-7S coprecipitates full length MDA-7 and reduces secretion of cotransfected MDA-7. mda-7 and mda-7s are coexpressed in all RNA preparations other than subcutaneous and lymph node metastasis where mda-7s expression is lacking. mda-7s expression is therefore linked to a non-metastatic phenotype."xsd:string |
| http://purl.uniprot.org/citations/15304100 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.0022-202x.2004.23321.x"xsd:string |
| http://purl.uniprot.org/citations/15304100 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.0022-202x.2004.23321.x"xsd:string |
| http://purl.uniprot.org/citations/15304100 | http://purl.uniprot.org/core/author | "Muller M."xsd:string |
| http://purl.uniprot.org/citations/15304100 | http://purl.uniprot.org/core/author | "Muller M."xsd:string |
| http://purl.uniprot.org/citations/15304100 | http://purl.uniprot.org/core/author | "Allen M."xsd:string |
| http://purl.uniprot.org/citations/15304100 | http://purl.uniprot.org/core/author | "Allen M."xsd:string |
| http://purl.uniprot.org/citations/15304100 | http://purl.uniprot.org/core/author | "Lucas T."xsd:string |
| http://purl.uniprot.org/citations/15304100 | http://purl.uniprot.org/core/author | "Lucas T."xsd:string |
| http://purl.uniprot.org/citations/15304100 | http://purl.uniprot.org/core/author | "Pehamberger H."xsd:string |
| http://purl.uniprot.org/citations/15304100 | http://purl.uniprot.org/core/author | "Pehamberger H."xsd:string |
| http://purl.uniprot.org/citations/15304100 | http://purl.uniprot.org/core/author | "Pratscher B."xsd:string |
| http://purl.uniprot.org/citations/15304100 | http://purl.uniprot.org/core/author | "Pratscher B."xsd:string |
| http://purl.uniprot.org/citations/15304100 | http://purl.uniprot.org/core/author | "Schofer C."xsd:string |
| http://purl.uniprot.org/citations/15304100 | http://purl.uniprot.org/core/author | "Schofer C."xsd:string |
| http://purl.uniprot.org/citations/15304100 | http://purl.uniprot.org/core/author | "Krepler C."xsd:string |
| http://purl.uniprot.org/citations/15304100 | http://purl.uniprot.org/core/author | "Krepler C."xsd:string |
| http://purl.uniprot.org/citations/15304100 | http://purl.uniprot.org/core/author | "Roka F."xsd:string |
| http://purl.uniprot.org/citations/15304100 | http://purl.uniprot.org/core/author | "Roka F."xsd:string |
| http://purl.uniprot.org/citations/15304100 | http://purl.uniprot.org/core/author | "Wacheck V."xsd:string |
| http://purl.uniprot.org/citations/15304100 | http://purl.uniprot.org/core/author | "Wacheck V."xsd:string |
| http://purl.uniprot.org/citations/15304100 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15304100 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |