| http://purl.uniprot.org/citations/15448690 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15448690 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15448690 | http://www.w3.org/2000/01/rdf-schema#comment | "The activation of an immune response requires recognition of microorganisms by host receptors. In drosophila, detection of Gram-positive bacteria is mediated by cooperation between the peptidoglycan-recognition protein-SA (PGRP-SA) and Gram-negative binding protein 1 (GNBP1) proteins. Here we show that some Gram-positive bacterial species activate an immune response in a PGRP-SA- and GNBP1-independent manner, indicating that alternative receptors exist. Consistent with this, we noted that PGRP-SD mutants were susceptible to some Gram-positive bacteria and that a loss-of-function mutation in PGRP-SD severely exacerbated the PGRP-SA and GNBP1 mutant phenotypes. These data indicate that PGRP-SD can function as a receptor for Gram-positive bacteria and shows partial redundancy with the PGRP-SA-GNBP1 complex."xsd:string |
| http://purl.uniprot.org/citations/15448690 | http://purl.org/dc/terms/identifier | "doi:10.1038/ni1123"xsd:string |
| http://purl.uniprot.org/citations/15448690 | http://purl.org/dc/terms/identifier | "doi:10.1038/ni1123"xsd:string |
| http://purl.uniprot.org/citations/15448690 | http://purl.uniprot.org/core/author | "Boneca I.G."xsd:string |
| http://purl.uniprot.org/citations/15448690 | http://purl.uniprot.org/core/author | "Boneca I.G."xsd:string |
| http://purl.uniprot.org/citations/15448690 | http://purl.uniprot.org/core/author | "Vignal C."xsd:string |
| http://purl.uniprot.org/citations/15448690 | http://purl.uniprot.org/core/author | "Vignal C."xsd:string |
| http://purl.uniprot.org/citations/15448690 | http://purl.uniprot.org/core/author | "Hoffmann J.A."xsd:string |
| http://purl.uniprot.org/citations/15448690 | http://purl.uniprot.org/core/author | "Hoffmann J.A."xsd:string |
| http://purl.uniprot.org/citations/15448690 | http://purl.uniprot.org/core/author | "Michel T."xsd:string |
| http://purl.uniprot.org/citations/15448690 | http://purl.uniprot.org/core/author | "Michel T."xsd:string |
| http://purl.uniprot.org/citations/15448690 | http://purl.uniprot.org/core/author | "Bischoff V."xsd:string |
| http://purl.uniprot.org/citations/15448690 | http://purl.uniprot.org/core/author | "Bischoff V."xsd:string |
| http://purl.uniprot.org/citations/15448690 | http://purl.uniprot.org/core/author | "Royet J."xsd:string |
| http://purl.uniprot.org/citations/15448690 | http://purl.uniprot.org/core/author | "Royet J."xsd:string |
| http://purl.uniprot.org/citations/15448690 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15448690 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/15448690 | http://purl.uniprot.org/core/name | "Nat. Immunol."xsd:string |
| http://purl.uniprot.org/citations/15448690 | http://purl.uniprot.org/core/name | "Nat. Immunol."xsd:string |
| http://purl.uniprot.org/citations/15448690 | http://purl.uniprot.org/core/pages | "1175-1180"xsd:string |
| http://purl.uniprot.org/citations/15448690 | http://purl.uniprot.org/core/pages | "1175-1180"xsd:string |
| http://purl.uniprot.org/citations/15448690 | http://purl.uniprot.org/core/title | "Function of the Drosophila pattern-recognition receptor PGRP-SD in the detection of Gram-positive bacteria."xsd:string |
| http://purl.uniprot.org/citations/15448690 | http://purl.uniprot.org/core/title | "Function of the Drosophila pattern-recognition receptor PGRP-SD in the detection of Gram-positive bacteria."xsd:string |