Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Expression of PCNA and Ki-67 in the rat submandibular gland after one year cadmium intoxication--a preliminary study.

Czykier E., Dzieciol J.

The aim of our study was to determine to what degree one-year exposure of female rats to cadmium at a dose of 5, 50 and 100 mg Cd/l affects cell proliferation in the submandibular gland, shown by PCNA and Ki-67 expression. In the present study, we found a positive nuclear reaction for PCNA in single cells in microscopic preparations of control rats. In Group I, an increase was observed in the number of PCNA-positive cells, compared to that in the control. In Group II, the number of PCNA-positive cells was markedly higher than that in Group I and in the control. In the submandibular glands of rats in Group III, the number of PCNA-positive cells was similar to that, found in Group II. However, Ki-67 expression was sporadically observed in control submandibular glands, but not in Groups I, II and III.

Rocz. Akad. Med. Bialymst. 49 Suppl 1:172-174(2004) [PubMed] [Europe PMC]

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again