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| http://purl.uniprot.org/citations/15689149 | http://www.w3.org/2000/01/rdf-schema#comment | "Human cytidine deaminase (CDA) is an enzyme prominent for its role in catalyzing metabolic processing of nucleoside-type anticancer and antiviral agents. It is thus a promising target for the development of small molecule therapeutic adjuvants. We report the first crystal structure of human CDA as a complex with a tight-binding inhibitor, diazepinone riboside 1. The structure reveals that inhibitor 1 is able to establish a canonical pi/pi-interaction with a key active site residue, Phe 137."xsd:string |
| http://purl.uniprot.org/citations/15689149 | http://purl.org/dc/terms/identifier | "doi:10.1021/jm0496279"xsd:string |
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| http://purl.uniprot.org/citations/15689149 | http://purl.uniprot.org/core/author | "Chung S.J."xsd:string |
| http://purl.uniprot.org/citations/15689149 | http://purl.uniprot.org/core/author | "Chung S.J."xsd:string |
| http://purl.uniprot.org/citations/15689149 | http://purl.uniprot.org/core/author | "Verdine G.L."xsd:string |
| http://purl.uniprot.org/citations/15689149 | http://purl.uniprot.org/core/author | "Verdine G.L."xsd:string |
| http://purl.uniprot.org/citations/15689149 | http://purl.uniprot.org/core/author | "Fromme J.C."xsd:string |
| http://purl.uniprot.org/citations/15689149 | http://purl.uniprot.org/core/author | "Fromme J.C."xsd:string |
| http://purl.uniprot.org/citations/15689149 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15689149 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15689149 | http://purl.uniprot.org/core/name | "J. Med. Chem."xsd:string |
| http://purl.uniprot.org/citations/15689149 | http://purl.uniprot.org/core/name | "J. Med. Chem."xsd:string |
| http://purl.uniprot.org/citations/15689149 | http://purl.uniprot.org/core/pages | "658-660"xsd:string |
| http://purl.uniprot.org/citations/15689149 | http://purl.uniprot.org/core/pages | "658-660"xsd:string |
| http://purl.uniprot.org/citations/15689149 | http://purl.uniprot.org/core/title | "Structure of human cytidine deaminase bound to a potent inhibitor."xsd:string |
| http://purl.uniprot.org/citations/15689149 | http://purl.uniprot.org/core/title | "Structure of human cytidine deaminase bound to a potent inhibitor."xsd:string |
| http://purl.uniprot.org/citations/15689149 | http://purl.uniprot.org/core/volume | "48"xsd:string |
| http://purl.uniprot.org/citations/15689149 | http://purl.uniprot.org/core/volume | "48"xsd:string |
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| http://purl.uniprot.org/citations/15689149 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15689149 |
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| http://purl.uniprot.org/citations/15689149 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/15689149 |