| http://purl.uniprot.org/citations/15733859 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15733859 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/15733859 | http://www.w3.org/2000/01/rdf-schema#comment | "Bcl-2 contains an unusually long loop between the first and the second helices. This loop has been shown to be highly flexible based on NMR and X-ray crystallographic analyses of this region. Bcl-2 is regulated at the posttranslational level through phosphorylation of specific residues within the flexible loop. The biological role and posttranslational modifications of the loop of Bcl-2 is currently unclear. FK-506 binding protein 38 (FKBP38) has been reported to interact with Bcl-2, suggesting that FKBP38 could act as a docking molecule to localize Bcl-2 at the mitochondrial membrane [Shirane, M. and Nakayama, K.I. (2003) Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosis. Nat. Cell Biol. 5, 28-37]. Here, we investigated the molecular interaction between FKBP38 and Bcl-2, and demonstrated that Bcl-2 interacts with FKBP38 through the unstructured loop, and the interaction appears to regulate phosphorylation in the loop of Bcl-2."xsd:string |
| http://purl.uniprot.org/citations/15733859 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2005.01.053"xsd:string |
| http://purl.uniprot.org/citations/15733859 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2005.01.053"xsd:string |
| http://purl.uniprot.org/citations/15733859 | http://purl.uniprot.org/core/author | "Chia J."xsd:string |
| http://purl.uniprot.org/citations/15733859 | http://purl.uniprot.org/core/author | "Chia J."xsd:string |
| http://purl.uniprot.org/citations/15733859 | http://purl.uniprot.org/core/author | "Kang C.B."xsd:string |
| http://purl.uniprot.org/citations/15733859 | http://purl.uniprot.org/core/author | "Kang C.B."xsd:string |
| http://purl.uniprot.org/citations/15733859 | http://purl.uniprot.org/core/author | "Yoon H.S."xsd:string |
| http://purl.uniprot.org/citations/15733859 | http://purl.uniprot.org/core/author | "Yoon H.S."xsd:string |
| http://purl.uniprot.org/citations/15733859 | http://purl.uniprot.org/core/author | "Tai J."xsd:string |
| http://purl.uniprot.org/citations/15733859 | http://purl.uniprot.org/core/author | "Tai J."xsd:string |
| http://purl.uniprot.org/citations/15733859 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15733859 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/15733859 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/15733859 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/15733859 | http://purl.uniprot.org/core/pages | "1469-1476"xsd:string |
| http://purl.uniprot.org/citations/15733859 | http://purl.uniprot.org/core/pages | "1469-1476"xsd:string |
| http://purl.uniprot.org/citations/15733859 | http://purl.uniprot.org/core/title | "The flexible loop of Bcl-2 is required for molecular interaction with immunosuppressant FK-506 binding protein 38 (FKBP38)."xsd:string |
| http://purl.uniprot.org/citations/15733859 | http://purl.uniprot.org/core/title | "The flexible loop of Bcl-2 is required for molecular interaction with immunosuppressant FK-506 binding protein 38 (FKBP38)."xsd:string |
| http://purl.uniprot.org/citations/15733859 | http://purl.uniprot.org/core/volume | "579"xsd:string |
| http://purl.uniprot.org/citations/15733859 | http://purl.uniprot.org/core/volume | "579"xsd:string |
| http://purl.uniprot.org/citations/15733859 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15733859 |
| http://purl.uniprot.org/citations/15733859 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/15733859 |