| http://purl.uniprot.org/citations/1600944 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1600944 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1600944 | http://www.w3.org/2000/01/rdf-schema#comment | "The Saccharomyces cerevisiae gene CDC6, whose protein product is required for DNA replication, is transcribed only in late G1 and S phases. We have discovered a critical reason why CDC6 expression is regulated in this fashion. Constitutive CDC6 transcription greatly delayed the initiation of M phase without effecting the G1-S transition or growth rate. This occurred in both fission and budding yeasts. The CDC6-induced M phase delay was dependent on the wee1/mik1 mitotic inhibitor kinases and was greatly accentuated in strains defective for the cdc25/MIH1 mitotic inducer phosphatases, indicating that CDC6 indirectly inhibits activation of the p34cdc2/CDC28 M phase kinase. Thus CDC6 appears to have an important and perhaps unique dual role in S phase, it is first required for the initiation of DNA replication and then actively participates in the suppression of nuclear division."xsd:string |
| http://purl.uniprot.org/citations/1600944 | http://purl.org/dc/terms/identifier | "doi:10.1002/j.1460-2075.1992.tb05276.x"xsd:string |
| http://purl.uniprot.org/citations/1600944 | http://purl.org/dc/terms/identifier | "doi:10.1002/j.1460-2075.1992.tb05276.x"xsd:string |
| http://purl.uniprot.org/citations/1600944 | http://purl.uniprot.org/core/author | "Russell P."xsd:string |
| http://purl.uniprot.org/citations/1600944 | http://purl.uniprot.org/core/author | "Russell P."xsd:string |
| http://purl.uniprot.org/citations/1600944 | http://purl.uniprot.org/core/author | "Bueno A."xsd:string |
| http://purl.uniprot.org/citations/1600944 | http://purl.uniprot.org/core/author | "Bueno A."xsd:string |
| http://purl.uniprot.org/citations/1600944 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
| http://purl.uniprot.org/citations/1600944 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
| http://purl.uniprot.org/citations/1600944 | http://purl.uniprot.org/core/name | "EMBO J."xsd:string |
| http://purl.uniprot.org/citations/1600944 | http://purl.uniprot.org/core/name | "EMBO J."xsd:string |
| http://purl.uniprot.org/citations/1600944 | http://purl.uniprot.org/core/pages | "2167-2176"xsd:string |
| http://purl.uniprot.org/citations/1600944 | http://purl.uniprot.org/core/pages | "2167-2176"xsd:string |
| http://purl.uniprot.org/citations/1600944 | http://purl.uniprot.org/core/title | "Dual functions of CDC6: a yeast protein required for DNA replication also inhibits nuclear division."xsd:string |
| http://purl.uniprot.org/citations/1600944 | http://purl.uniprot.org/core/title | "Dual functions of CDC6: a yeast protein required for DNA replication also inhibits nuclear division."xsd:string |
| http://purl.uniprot.org/citations/1600944 | http://purl.uniprot.org/core/volume | "11"xsd:string |
| http://purl.uniprot.org/citations/1600944 | http://purl.uniprot.org/core/volume | "11"xsd:string |
| http://purl.uniprot.org/citations/1600944 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1600944 |
| http://purl.uniprot.org/citations/1600944 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1600944 |
| http://purl.uniprot.org/citations/1600944 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/1600944 |
| http://purl.uniprot.org/citations/1600944 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/1600944 |
| http://purl.uniprot.org/uniprot/P09119 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/1600944 |
| http://purl.uniprot.org/uniprot/P09119#attribution-D147027EAFD5F32E82D5C4E0245A3516 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/1600944 |