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http://purl.uniprot.org/citations/16019082http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16019082http://www.w3.org/2000/01/rdf-schema#comment"Excitotoxicity is a cell death caused by excessive exposure to glutamate (Glu), contributing to neuronal degeneration in many acute and chronic CNS diseases. We explored the role of fractalkine/CX3CL1 on survival of hippocampal neurons exposed to excitotoxic doses of Glu. We found that: CX3CL1 reduces excitotoxicity when co-applied with Glu, through the activation of the ERK1/2 and PI3K/Akt pathways, or administered up to 8 h after Glu insult; CX3CL1 reduces the Glu-activated whole-cell current through mechanisms dependent on intracellular Ca2+; CX3CL1 is released from hippocampal cells after excitotoxic insult, likely providing an endogenous protective mechanism against excitotoxic cell death."xsd:string
http://purl.uniprot.org/citations/16019082http://purl.org/dc/terms/identifier"doi:10.1016/j.jneuroim.2005.03.023"xsd:string
http://purl.uniprot.org/citations/16019082http://purl.uniprot.org/core/author"Eusebi F."xsd:string
http://purl.uniprot.org/citations/16019082http://purl.uniprot.org/core/author"Catalano M."xsd:string
http://purl.uniprot.org/citations/16019082http://purl.uniprot.org/core/author"Ragozzino D."xsd:string
http://purl.uniprot.org/citations/16019082http://purl.uniprot.org/core/author"Ciotti M.T."xsd:string
http://purl.uniprot.org/citations/16019082http://purl.uniprot.org/core/author"Limatola C."xsd:string
http://purl.uniprot.org/citations/16019082http://purl.uniprot.org/core/author"Di Angelantonio S."xsd:string
http://purl.uniprot.org/citations/16019082http://purl.uniprot.org/core/author"Lauro C."xsd:string
http://purl.uniprot.org/citations/16019082http://purl.uniprot.org/core/author"Bertollini C."xsd:string
http://purl.uniprot.org/citations/16019082http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/16019082http://purl.uniprot.org/core/name"J Neuroimmunol"xsd:string
http://purl.uniprot.org/citations/16019082http://purl.uniprot.org/core/pages"19-28"xsd:string
http://purl.uniprot.org/citations/16019082http://purl.uniprot.org/core/title"Chemokine CX3CL1 protects rat hippocampal neurons against glutamate-mediated excitotoxicity."xsd:string
http://purl.uniprot.org/citations/16019082http://purl.uniprot.org/core/volume"166"xsd:string
http://purl.uniprot.org/citations/16019082http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/16019082
http://purl.uniprot.org/citations/16019082http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/16019082
http://purl.uniprot.org/uniprot/P49238#attribution-66B2484636B397EC186E7B074509F7D5http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/16019082
http://purl.uniprot.org/uniprot/O55145#attribution-3BB253415E7513DBC520C7D696EC4C0Ahttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/16019082
http://purl.uniprot.org/uniprot/#_A0A8I5Y6B8-mappedCitation-16019082http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16019082
http://purl.uniprot.org/uniprot/#_O55145-mappedCitation-16019082http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16019082
http://purl.uniprot.org/uniprot/O55145http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/16019082
http://purl.uniprot.org/uniprot/A0A8I5Y6B8http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/16019082