http://purl.uniprot.org/citations/16019082 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/16019082 | http://www.w3.org/2000/01/rdf-schema#comment | "Excitotoxicity is a cell death caused by excessive exposure to glutamate (Glu), contributing to neuronal degeneration in many acute and chronic CNS diseases. We explored the role of fractalkine/CX3CL1 on survival of hippocampal neurons exposed to excitotoxic doses of Glu. We found that: CX3CL1 reduces excitotoxicity when co-applied with Glu, through the activation of the ERK1/2 and PI3K/Akt pathways, or administered up to 8 h after Glu insult; CX3CL1 reduces the Glu-activated whole-cell current through mechanisms dependent on intracellular Ca2+; CX3CL1 is released from hippocampal cells after excitotoxic insult, likely providing an endogenous protective mechanism against excitotoxic cell death."xsd:string |
http://purl.uniprot.org/citations/16019082 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.jneuroim.2005.03.023"xsd:string |
http://purl.uniprot.org/citations/16019082 | http://purl.uniprot.org/core/author | "Eusebi F."xsd:string |
http://purl.uniprot.org/citations/16019082 | http://purl.uniprot.org/core/author | "Catalano M."xsd:string |
http://purl.uniprot.org/citations/16019082 | http://purl.uniprot.org/core/author | "Ragozzino D."xsd:string |
http://purl.uniprot.org/citations/16019082 | http://purl.uniprot.org/core/author | "Ciotti M.T."xsd:string |
http://purl.uniprot.org/citations/16019082 | http://purl.uniprot.org/core/author | "Limatola C."xsd:string |
http://purl.uniprot.org/citations/16019082 | http://purl.uniprot.org/core/author | "Di Angelantonio S."xsd:string |
http://purl.uniprot.org/citations/16019082 | http://purl.uniprot.org/core/author | "Lauro C."xsd:string |
http://purl.uniprot.org/citations/16019082 | http://purl.uniprot.org/core/author | "Bertollini C."xsd:string |
http://purl.uniprot.org/citations/16019082 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
http://purl.uniprot.org/citations/16019082 | http://purl.uniprot.org/core/name | "J Neuroimmunol"xsd:string |
http://purl.uniprot.org/citations/16019082 | http://purl.uniprot.org/core/pages | "19-28"xsd:string |
http://purl.uniprot.org/citations/16019082 | http://purl.uniprot.org/core/title | "Chemokine CX3CL1 protects rat hippocampal neurons against glutamate-mediated excitotoxicity."xsd:string |
http://purl.uniprot.org/citations/16019082 | http://purl.uniprot.org/core/volume | "166"xsd:string |
http://purl.uniprot.org/citations/16019082 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16019082 |
http://purl.uniprot.org/citations/16019082 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16019082 |
http://purl.uniprot.org/uniprot/P49238#attribution-66B2484636B397EC186E7B074509F7D5 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/16019082 |
http://purl.uniprot.org/uniprot/O55145#attribution-3BB253415E7513DBC520C7D696EC4C0A | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/16019082 |
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http://purl.uniprot.org/uniprot/#_O55145-mappedCitation-16019082 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/16019082 |
http://purl.uniprot.org/uniprot/O55145 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/16019082 |
http://purl.uniprot.org/uniprot/A0A8I5Y6B8 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/16019082 |