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http://purl.uniprot.org/citations/16142217http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16142217http://www.w3.org/2000/01/rdf-schema#comment"Unlike other positive-stranded RNA viruses that use either a 5'-cap structure or an internal ribosome entry site to direct translation of their messenger RNA, calicivirus translation is dependent on the presence of a protein covalently linked to the 5' end of the viral genome (VPg). We have shown a direct interaction of the calicivirus VPg with the cap-binding protein eIF 4 E. This interaction is required for calicivirus mRNA translation, as sequestration of eIF 4 E by 4 E-BP 1 inhibits translation. Functional analysis has shown that VPg does not interfere with the interaction between eIF 4 E and the cap structure or 4 E-BP 1, suggesting that VPg binds to eIF 4 E at a different site from both cap and 4 E-BP 1. This work lends support to the idea that calicivirus VPg acts as a novel 'cap substitute' during initiation of translation on virus mRNA."xsd:string
http://purl.uniprot.org/citations/16142217http://purl.org/dc/terms/identifier"doi:10.1038/sj.embor.7400510"xsd:string
http://purl.uniprot.org/citations/16142217http://purl.uniprot.org/core/author"Chaudhry Y."xsd:string
http://purl.uniprot.org/citations/16142217http://purl.uniprot.org/core/author"Laliberte J.F."xsd:string
http://purl.uniprot.org/citations/16142217http://purl.uniprot.org/core/author"Goodfellow I."xsd:string
http://purl.uniprot.org/citations/16142217http://purl.uniprot.org/core/author"Gerondopoulos A."xsd:string
http://purl.uniprot.org/citations/16142217http://purl.uniprot.org/core/author"Roberts L."xsd:string
http://purl.uniprot.org/citations/16142217http://purl.uniprot.org/core/author"Gioldasi I."xsd:string
http://purl.uniprot.org/citations/16142217http://purl.uniprot.org/core/author"Labrie L."xsd:string
http://purl.uniprot.org/citations/16142217http://purl.uniprot.org/core/author"Natoni A."xsd:string
http://purl.uniprot.org/citations/16142217http://purl.uniprot.org/core/date"2005"xsd:gYear
http://purl.uniprot.org/citations/16142217http://purl.uniprot.org/core/name"EMBO Rep"xsd:string
http://purl.uniprot.org/citations/16142217http://purl.uniprot.org/core/pages"968-972"xsd:string
http://purl.uniprot.org/citations/16142217http://purl.uniprot.org/core/title"Calicivirus translation initiation requires an interaction between VPg and eIF 4 E."xsd:string
http://purl.uniprot.org/citations/16142217http://purl.uniprot.org/core/volume"6"xsd:string
http://purl.uniprot.org/citations/16142217http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/16142217
http://purl.uniprot.org/citations/16142217http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/16142217
http://purl.uniprot.org/uniprot/Q60876#attribution-63025D61C98B6D9B558742A5B5613EE4http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/16142217
http://purl.uniprot.org/uniprot/Q60876#attribution-85E9E7027685932D3DB001394BAB4D20http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/16142217
http://purl.uniprot.org/uniprot/#_A0A0G2JG98-mappedCitation-16142217http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16142217
http://purl.uniprot.org/uniprot/#_A0A0G2JGT5-mappedCitation-16142217http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16142217
http://purl.uniprot.org/uniprot/#_A0A0G2JH04-mappedCitation-16142217http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16142217
http://purl.uniprot.org/uniprot/#_P63073-mappedCitation-16142217http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16142217
http://purl.uniprot.org/uniprot/#_A0A0G2JFB4-mappedCitation-16142217http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/16142217