| http://purl.uniprot.org/citations/16221885 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16221885 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16221885 | http://www.w3.org/2000/01/rdf-schema#comment | "Ubiquitously expressed transcript (UXT) is a prefoldinlike protein that has been suggested to be involved in human tumorigenesis. Here, we have found that UXT is overexpressed in a number of human tumor tissues but not in the matching normal tissues. We demonstrate that UXT is located in human centrosomes and is associated with gamma-tubulin. In addition, overexpression of UXT disrupts centrosome structure. Furthermore, abrogation of UXT protein expression by small interfering RNA knockdown leads to cell death. Together, our findings suggest that UXT is a component of centrosome and is essential for cell viability. We propose that UXT may facilitate transformation by corrupting regulated centrosome functions."xsd:string |
| http://purl.uniprot.org/citations/16221885 | http://purl.org/dc/terms/identifier | "doi:10.1091/mbc.e05-08-0705"xsd:string |
| http://purl.uniprot.org/citations/16221885 | http://purl.org/dc/terms/identifier | "doi:10.1091/mbc.e05-08-0705"xsd:string |
| http://purl.uniprot.org/citations/16221885 | http://purl.uniprot.org/core/author | "Liu Q."xsd:string |
| http://purl.uniprot.org/citations/16221885 | http://purl.uniprot.org/core/author | "Liu Q."xsd:string |
| http://purl.uniprot.org/citations/16221885 | http://purl.uniprot.org/core/author | "Richter M."xsd:string |
| http://purl.uniprot.org/citations/16221885 | http://purl.uniprot.org/core/author | "Richter M."xsd:string |
| http://purl.uniprot.org/citations/16221885 | http://purl.uniprot.org/core/author | "Wang Q."xsd:string |
| http://purl.uniprot.org/citations/16221885 | http://purl.uniprot.org/core/author | "Wang Q."xsd:string |
| http://purl.uniprot.org/citations/16221885 | http://purl.uniprot.org/core/author | "Zhao H."xsd:string |
| http://purl.uniprot.org/citations/16221885 | http://purl.uniprot.org/core/author | "Zhao H."xsd:string |
| http://purl.uniprot.org/citations/16221885 | http://purl.uniprot.org/core/author | "Zhang H."xsd:string |
| http://purl.uniprot.org/citations/16221885 | http://purl.uniprot.org/core/author | "Zhang H."xsd:string |
| http://purl.uniprot.org/citations/16221885 | http://purl.uniprot.org/core/author | "Du X."xsd:string |
| http://purl.uniprot.org/citations/16221885 | http://purl.uniprot.org/core/author | "Du X."xsd:string |
| http://purl.uniprot.org/citations/16221885 | http://purl.uniprot.org/core/author | "Greene M.I."xsd:string |
| http://purl.uniprot.org/citations/16221885 | http://purl.uniprot.org/core/author | "Greene M.I."xsd:string |
| http://purl.uniprot.org/citations/16221885 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/16221885 | http://purl.uniprot.org/core/date | "2005"xsd:gYear |
| http://purl.uniprot.org/citations/16221885 | http://purl.uniprot.org/core/name | "Mol. Biol. Cell"xsd:string |
| http://purl.uniprot.org/citations/16221885 | http://purl.uniprot.org/core/name | "Mol. Biol. Cell"xsd:string |
| http://purl.uniprot.org/citations/16221885 | http://purl.uniprot.org/core/pages | "5857-5865"xsd:string |
| http://purl.uniprot.org/citations/16221885 | http://purl.uniprot.org/core/pages | "5857-5865"xsd:string |