http://purl.uniprot.org/citations/1627459 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/1627459 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/1627459 | http://www.w3.org/2000/01/rdf-schema#comment | "The L1 cell adhesion molecule was initially identified and characterized in mouse as a cell-surface glycoprotein that mediates neuron-neuron and neuron-Schwann cell adhesion. We have characterized L1 in humans using cDNA structural and mRNA expression analyses. We present the entire coding sequence for human L1, which predicts a 1253-amino acid protein displaying a signal sequence, transmembrane segment, RGD sequence, and potential glycosylation and phosphorylation sites. Nucleotide and deduced amino acid sequence identities between human and mouse L1 are 85% and 87%, respectively. In contrast, the amino acid identity between human L1 and the L1-related molecule chicken Ng-CAM is only 45%. Using Northern blot analyses, a single L1 transcript of 5.5 kb is detected in human fetal brain and in neuroblastoma (IMR-32) and retinoblastoma (Y-79) cell lines. L1 is also expressed in the rhabdomyosarcoma cell lines RD and A-204, which display several muscle characteristics. Two forms of L1, which differ by the presence or absence of a 12-bp cytoplasmic segment, are expressed in both human and mouse. This segment is encoded by a single exon that can be alternately spliced to give rise to the two forms, which appear to be expressed in tissue-specific patterns."xsd:string |
http://purl.uniprot.org/citations/1627459 | http://purl.org/dc/terms/identifier | "doi:10.1007/bf02919404"xsd:string |
http://purl.uniprot.org/citations/1627459 | http://purl.org/dc/terms/identifier | "doi:10.1007/bf02919404"xsd:string |
http://purl.uniprot.org/citations/1627459 | http://purl.uniprot.org/core/author | "Hemperly J.J."xsd:string |
http://purl.uniprot.org/citations/1627459 | http://purl.uniprot.org/core/author | "Hemperly J.J."xsd:string |
http://purl.uniprot.org/citations/1627459 | http://purl.uniprot.org/core/author | "Reid R.A."xsd:string |
http://purl.uniprot.org/citations/1627459 | http://purl.uniprot.org/core/author | "Reid R.A."xsd:string |
http://purl.uniprot.org/citations/1627459 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
http://purl.uniprot.org/citations/1627459 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
http://purl.uniprot.org/citations/1627459 | http://purl.uniprot.org/core/name | "J. Mol. Neurosci."xsd:string |
http://purl.uniprot.org/citations/1627459 | http://purl.uniprot.org/core/name | "J. Mol. Neurosci."xsd:string |
http://purl.uniprot.org/citations/1627459 | http://purl.uniprot.org/core/pages | "127-135"xsd:string |
http://purl.uniprot.org/citations/1627459 | http://purl.uniprot.org/core/pages | "127-135"xsd:string |
http://purl.uniprot.org/citations/1627459 | http://purl.uniprot.org/core/title | "Variants of human L1 cell adhesion molecule arise through alternate splicing of RNA."xsd:string |
http://purl.uniprot.org/citations/1627459 | http://purl.uniprot.org/core/title | "Variants of human L1 cell adhesion molecule arise through alternate splicing of RNA."xsd:string |
http://purl.uniprot.org/citations/1627459 | http://purl.uniprot.org/core/volume | "3"xsd:string |
http://purl.uniprot.org/citations/1627459 | http://purl.uniprot.org/core/volume | "3"xsd:string |
http://purl.uniprot.org/citations/1627459 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1627459 |
http://purl.uniprot.org/citations/1627459 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1627459 |
http://purl.uniprot.org/citations/1627459 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/1627459 |
http://purl.uniprot.org/citations/1627459 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/1627459 |
http://purl.uniprot.org/uniprot/P32004 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/1627459 |
http://purl.uniprot.org/uniprot/P32004#attribution-B9FA295F57FF12534DED8012647FC308 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/1627459 |