| http://purl.uniprot.org/citations/1671824 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1671824 | http://www.w3.org/2000/01/rdf-schema#comment | "Arylsulfatases A (EC 3.1.6.1) and B (EC 3.1.6.12) are lysosomal enzymes that can remove sulfate groups from sulfatides and sulfo-glycosaminoglycans, respectively. The activities of these enzymes in cerebral cortex and in spinal cord of developing rat pups were measured. The tissues were homogenized and the arylsulfatases A and B in the soluble fraction were separated from each other by anion exchange chromatography on DE-52 cellulose. Subsequently, the enzyme activities were assayed with p-nitrocatechol sulfate as substrate at 37 degrees C and pH 5.6. We observed a developmental profile of arylsulfatase A, similar to that previously reported for cerebroside sulfatase (EC 3.1.6.8; (Van der Pal et al. (1990) Biochim. Biophys. Acta 1043, 91-96]. The activity of arylsulfatase A increased gradually during development, whereas arylsulfatase B rose more steeply, peaked around day 15 and declined thereafter. As a consequence the ratio between B and A forms of arylsulfatase dropped from about 4 in 1-week-old pups to 2.2 (cortex) and 0.7 (cord) in 7-week-old rat pups."xsd:string |
| http://purl.uniprot.org/citations/1671824 | http://purl.org/dc/terms/identifier | "doi:10.1016/0005-2760(91)90288-s"xsd:string |
| http://purl.uniprot.org/citations/1671824 | http://purl.uniprot.org/core/author | "Lopes-Cardozo M."xsd:string |
| http://purl.uniprot.org/citations/1671824 | http://purl.uniprot.org/core/author | "Klein W."xsd:string |
| http://purl.uniprot.org/citations/1671824 | http://purl.uniprot.org/core/author | "van Golde L.M."xsd:string |
| http://purl.uniprot.org/citations/1671824 | http://purl.uniprot.org/core/author | "van der Pal R.H."xsd:string |
| http://purl.uniprot.org/citations/1671824 | http://purl.uniprot.org/core/date | "1991"xsd:gYear |
| http://purl.uniprot.org/citations/1671824 | http://purl.uniprot.org/core/name | "Biochim Biophys Acta"xsd:string |
| http://purl.uniprot.org/citations/1671824 | http://purl.uniprot.org/core/pages | "315-320"xsd:string |
| http://purl.uniprot.org/citations/1671824 | http://purl.uniprot.org/core/title | "Developmental profiles of arylsulfatases A and B in rat cerebral cortex and spinal cord."xsd:string |
| http://purl.uniprot.org/citations/1671824 | http://purl.uniprot.org/core/volume | "1081"xsd:string |
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