| http://purl.uniprot.org/citations/16781730 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16781730 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/16781730 | http://www.w3.org/2000/01/rdf-schema#comment | "Genetic studies in Saccharomyces cerevisiae predict that the mismatch repair (MMR) factor MSH2-MSH3 binds and stabilizes branched recombination intermediates that form during single strand annealing and gene conversion. To test this model, we constructed a series of DNA substrates that are predicted to form during these recombination events. We show in an electrophoretic mobility shift assay that S. cerevisiae MSH2-MSH3 specifically binds branched DNA substrates containing 3' single-stranded DNA and that ATP stimulates its release from these substrates. Chemical footprinting analyses indicate that MSH2-MSH3 specifically binds at the double-strand/single-strand junction of branched substrates, alters its conformation and opens up the junction. Therefore, MSH2-MSH3 binding to its substrates creates a unique nucleoprotein structure that may signal downstream steps in repair that include interactions with MMR and nucleotide excision repair factors."xsd:string |
| http://purl.uniprot.org/citations/16781730 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.jmb.2006.05.032"xsd:string |
| http://purl.uniprot.org/citations/16781730 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.jmb.2006.05.032"xsd:string |
| http://purl.uniprot.org/citations/16781730 | http://purl.uniprot.org/core/author | "Alani E."xsd:string |
| http://purl.uniprot.org/citations/16781730 | http://purl.uniprot.org/core/author | "Alani E."xsd:string |
| http://purl.uniprot.org/citations/16781730 | http://purl.uniprot.org/core/author | "Surtees J.A."xsd:string |
| http://purl.uniprot.org/citations/16781730 | http://purl.uniprot.org/core/author | "Surtees J.A."xsd:string |
| http://purl.uniprot.org/citations/16781730 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16781730 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/16781730 | http://purl.uniprot.org/core/name | "J. Mol. Biol."xsd:string |
| http://purl.uniprot.org/citations/16781730 | http://purl.uniprot.org/core/name | "J. Mol. Biol."xsd:string |
| http://purl.uniprot.org/citations/16781730 | http://purl.uniprot.org/core/pages | "523-536"xsd:string |
| http://purl.uniprot.org/citations/16781730 | http://purl.uniprot.org/core/pages | "523-536"xsd:string |
| http://purl.uniprot.org/citations/16781730 | http://purl.uniprot.org/core/title | "Mismatch repair factor MSH2-MSH3 binds and alters the conformation of branched DNA structures predicted to form during genetic recombination."xsd:string |
| http://purl.uniprot.org/citations/16781730 | http://purl.uniprot.org/core/title | "Mismatch repair factor MSH2-MSH3 binds and alters the conformation of branched DNA structures predicted to form during genetic recombination."xsd:string |
| http://purl.uniprot.org/citations/16781730 | http://purl.uniprot.org/core/volume | "360"xsd:string |
| http://purl.uniprot.org/citations/16781730 | http://purl.uniprot.org/core/volume | "360"xsd:string |
| http://purl.uniprot.org/citations/16781730 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16781730 |
| http://purl.uniprot.org/citations/16781730 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/16781730 |
| http://purl.uniprot.org/citations/16781730 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16781730 |
| http://purl.uniprot.org/citations/16781730 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/16781730 |
| http://purl.uniprot.org/uniprot/P25847 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/16781730 |
| http://purl.uniprot.org/uniprot/P25336 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/16781730 |