| http://purl.uniprot.org/citations/1692159 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1692159 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1692159 | http://www.w3.org/2000/01/rdf-schema#comment | "Chronic granulomatous diseases (CGDs) are characterized by recurrent infections resulting from impaired superoxide production by a phagocytic cell, nicotinamide adenine dinucleotide phosphate (reduced) (NADPH) oxidase. Complementary DNAs were cloned that encode the 67-kilodalton (kD) cytosolic oxidase factor (p67), which is deficient in 5% of CGD patients. Recombinant p67 (r-p67) partially restored NADPH oxidase activity to p67-deficient neutrophil cytosol from these patients. The p67 cDNA encodes a 526-amino acid protein with acidic middle and carboxyl-terminal domains that are similar to a sequence motif found in the noncatalytic domain of src-related tyrosine kinases. This motif was recently noted in phospholipase C-gamma, nonerythroid alpha-spectrin (fodrin), p21ras-guanosine triphophatase-activating protein (GAP), myosin-1 isoforms, yeast proteins cdc-25 and fus-1, and the 47-kD phagocyte oxidase factor (p47), which suggests the possibility of common regulatory features."xsd:string |
| http://purl.uniprot.org/citations/1692159 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1692159"xsd:string |
| http://purl.uniprot.org/citations/1692159 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1692159"xsd:string |
| http://purl.uniprot.org/citations/1692159 | http://purl.uniprot.org/core/author | "Malech H.L."xsd:string |
| http://purl.uniprot.org/citations/1692159 | http://purl.uniprot.org/core/author | "Malech H.L."xsd:string |
| http://purl.uniprot.org/citations/1692159 | http://purl.uniprot.org/core/author | "Leto T.L."xsd:string |
| http://purl.uniprot.org/citations/1692159 | http://purl.uniprot.org/core/author | "Leto T.L."xsd:string |
| http://purl.uniprot.org/citations/1692159 | http://purl.uniprot.org/core/author | "Gallin J.I."xsd:string |
| http://purl.uniprot.org/citations/1692159 | http://purl.uniprot.org/core/author | "Gallin J.I."xsd:string |
| http://purl.uniprot.org/citations/1692159 | http://purl.uniprot.org/core/author | "Clark R.A."xsd:string |
| http://purl.uniprot.org/citations/1692159 | http://purl.uniprot.org/core/author | "Clark R.A."xsd:string |
| http://purl.uniprot.org/citations/1692159 | http://purl.uniprot.org/core/author | "Nauseef W.M."xsd:string |
| http://purl.uniprot.org/citations/1692159 | http://purl.uniprot.org/core/author | "Nauseef W.M."xsd:string |
| http://purl.uniprot.org/citations/1692159 | http://purl.uniprot.org/core/author | "Nunoi H."xsd:string |
| http://purl.uniprot.org/citations/1692159 | http://purl.uniprot.org/core/author | "Nunoi H."xsd:string |
| http://purl.uniprot.org/citations/1692159 | http://purl.uniprot.org/core/author | "Volpp B.D."xsd:string |
| http://purl.uniprot.org/citations/1692159 | http://purl.uniprot.org/core/author | "Volpp B.D."xsd:string |
| http://purl.uniprot.org/citations/1692159 | http://purl.uniprot.org/core/author | "Lomax K.J."xsd:string |
| http://purl.uniprot.org/citations/1692159 | http://purl.uniprot.org/core/author | "Lomax K.J."xsd:string |
| http://purl.uniprot.org/citations/1692159 | http://purl.uniprot.org/core/author | "Sechler J.M.G."xsd:string |
| http://purl.uniprot.org/citations/1692159 | http://purl.uniprot.org/core/author | "Sechler J.M.G."xsd:string |
| http://purl.uniprot.org/citations/1692159 | http://purl.uniprot.org/core/date | "1990"xsd:gYear |
| http://purl.uniprot.org/citations/1692159 | http://purl.uniprot.org/core/date | "1990"xsd:gYear |