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http://purl.uniprot.org/citations/16962593http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16962593http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/16962593http://www.w3.org/2000/01/rdf-schema#comment"Rab14 localizes to the Golgi/TGN and to early endosomes, but its biological function remains unclear. By structural modeling, we identified Rab14-specific residues and established a close relationship between the Rab2/Rab4/Rab14, Rab11/25 and Rab39 sub-groups within the Rab protein family. By quantitative confocal microscopy and by density centrifugation we show that Rab14 is part of the early endosomal AP-1 microdomain. Overexpression of a dominant-negative Rab14 GTP-binding mutant that solely localizes to the Golgi donor compartment accelerated EGF degradation. We suggest that the AP-1 microdomain represents the interconnecting compartment in which Rab14 vesicles cycle between early endosomes and the Golgi cisternae."xsd:string
http://purl.uniprot.org/citations/16962593http://purl.org/dc/terms/identifier"doi:10.1016/j.febslet.2006.08.053"xsd:string
http://purl.uniprot.org/citations/16962593http://purl.org/dc/terms/identifier"doi:10.1016/j.febslet.2006.08.053"xsd:string
http://purl.uniprot.org/citations/16962593http://purl.uniprot.org/core/author"Frickey T."xsd:string
http://purl.uniprot.org/citations/16962593http://purl.uniprot.org/core/author"Frickey T."xsd:string
http://purl.uniprot.org/citations/16962593http://purl.uniprot.org/core/author"Proikas-Cezanne T."xsd:string
http://purl.uniprot.org/citations/16962593http://purl.uniprot.org/core/author"Proikas-Cezanne T."xsd:string
http://purl.uniprot.org/citations/16962593http://purl.uniprot.org/core/author"Nordheim A."xsd:string
http://purl.uniprot.org/citations/16962593http://purl.uniprot.org/core/author"Nordheim A."xsd:string
http://purl.uniprot.org/citations/16962593http://purl.uniprot.org/core/author"Gaugel A."xsd:string
http://purl.uniprot.org/citations/16962593http://purl.uniprot.org/core/author"Gaugel A."xsd:string
http://purl.uniprot.org/citations/16962593http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/16962593http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/16962593http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/16962593http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/16962593http://purl.uniprot.org/core/pages"5241-5246"xsd:string
http://purl.uniprot.org/citations/16962593http://purl.uniprot.org/core/pages"5241-5246"xsd:string
http://purl.uniprot.org/citations/16962593http://purl.uniprot.org/core/title"Rab14 is part of the early endosomal clathrin-coated TGN microdomain."xsd:string
http://purl.uniprot.org/citations/16962593http://purl.uniprot.org/core/title"Rab14 is part of the early endosomal clathrin-coated TGN microdomain."xsd:string
http://purl.uniprot.org/citations/16962593http://purl.uniprot.org/core/volume"580"xsd:string
http://purl.uniprot.org/citations/16962593http://purl.uniprot.org/core/volume"580"xsd:string
http://purl.uniprot.org/citations/16962593http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/16962593
http://purl.uniprot.org/citations/16962593http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/16962593