| http://purl.uniprot.org/citations/17097608 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17097608 | http://www.w3.org/2000/01/rdf-schema#comment | "Although delta-catenin/neural plakophilin-related armadillo protein (NPRAP) was reported to interact with presenilin-1 (PS-1), the effects of PS-1 on delta-catenin have not been established. In this study, we report that overexpression of PS-1 inhibits the delta-catenin-induced dendrite-like morphological changes in NIH 3T3 cells and promotes delta-catenin processing and turnover. The effects of PS-1 on endogenous delta-catenin processing were confirmed in hippocampal neurons overexpressing PS-1, as well as in the transgenic mice expressing the disease-causing mutant PS-1 (M146V). In addition, disease-causing mutant PS-1 (M146V and L286V) enhanced delta-catenin processing, whereas PS-1/gamma-secretase inhibitors could block the formation of processed forms of delta-catenin. Together, our findings suggest that PS-1 can affect delta-catenin-induced morphogenesis possibly through the regulation of its processing and stability."xsd:string |
| http://purl.uniprot.org/citations/17097608 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2006.10.135"xsd:string |
| http://purl.uniprot.org/citations/17097608 | http://purl.uniprot.org/core/author | "Kim K."xsd:string |
| http://purl.uniprot.org/citations/17097608 | http://purl.uniprot.org/core/author | "Kim K.K."xsd:string |
| http://purl.uniprot.org/citations/17097608 | http://purl.uniprot.org/core/author | "Kim J.S."xsd:string |
| http://purl.uniprot.org/citations/17097608 | http://purl.uniprot.org/core/author | "Kim H."xsd:string |
| http://purl.uniprot.org/citations/17097608 | http://purl.uniprot.org/core/author | "Lu Q."xsd:string |
| http://purl.uniprot.org/citations/17097608 | http://purl.uniprot.org/core/author | "Jin Y.H."xsd:string |
| http://purl.uniprot.org/citations/17097608 | http://purl.uniprot.org/core/author | "Bareiss S."xsd:string |
| http://purl.uniprot.org/citations/17097608 | http://purl.uniprot.org/core/author | "Han J.R."xsd:string |
| http://purl.uniprot.org/citations/17097608 | http://purl.uniprot.org/core/author | "Tatum R."xsd:string |
| http://purl.uniprot.org/citations/17097608 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/17097608 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
| http://purl.uniprot.org/citations/17097608 | http://purl.uniprot.org/core/pages | "903-908"xsd:string |
| http://purl.uniprot.org/citations/17097608 | http://purl.uniprot.org/core/title | "Presenilin-1 inhibits delta-catenin-induced cellular branching and promotes delta-catenin processing and turnover."xsd:string |
| http://purl.uniprot.org/citations/17097608 | http://purl.uniprot.org/core/volume | "351"xsd:string |
| http://purl.uniprot.org/citations/17097608 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17097608 |
| http://purl.uniprot.org/citations/17097608 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17097608 |
| http://purl.uniprot.org/uniprot/O35927#attribution-A9DAADB8864FD112B8A60D1112693AD8 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/17097608 |
| http://purl.uniprot.org/uniprot/Q61144#attribution-6551B3E3C9C3B519ACD3FC82E15438AA | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/17097608 |
| http://purl.uniprot.org/uniprot/P49769#attribution-0FE295D8E28B50EF9FAE3B4157107428 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/17097608 |
| http://purl.uniprot.org/uniprot/P49769#attribution-A9DAADB8864FD112B8A60D1112693AD8 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/17097608 |
| http://purl.uniprot.org/uniprot/#_A0A0R4J1F2-mappedCitation-17097608 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17097608 |
| http://purl.uniprot.org/uniprot/#_D3Z0X1-mappedCitation-17097608 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17097608 |