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http://purl.uniprot.org/citations/1714723http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1714723http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1714723http://www.w3.org/2000/01/rdf-schema#comment"Complementary DNA coding for thromboxane A synthase was amplified by polymerase chain reaction using primers synthesized according to the partial amino acid sequences of human platelet thromboxane A synthase (Nüsing, R., Schneider-Voss, S., and Ullrich, V. (1990) Arch. Biochem. Biophys. 280, 325-330) and cloned into pBluescript SK II(-). The primary structure of human platelet enzyme was deduced from the nucleotide sequence of the cDNA. The enzyme is composed of 533 amino acids with a molecular weight of 60,487. The primary structure of the enzyme exhibited a 34-36% homology to the amino acid sequences of cytochrome P450s classified in the P450 III gene family. The highly conserved cysteine-containing sequence involved in the heme-binding site of P450 was found near the carboxyl terminus (residues 472-492). The size of the major thromboxane A synthase mRNA from human platelets and human erythroleukemia cells was estimated to be approximately 2.2 kilobases by RNA blot analysis."xsd:string
http://purl.uniprot.org/citations/1714723http://purl.org/dc/terms/identifier"doi:10.1016/0006-291x(91)91060-p"xsd:string
http://purl.uniprot.org/citations/1714723http://purl.org/dc/terms/identifier"doi:10.1016/0006-291x(91)91060-p"xsd:string
http://purl.uniprot.org/citations/1714723http://purl.uniprot.org/core/author"Ihara H."xsd:string
http://purl.uniprot.org/citations/1714723http://purl.uniprot.org/core/author"Ihara H."xsd:string
http://purl.uniprot.org/citations/1714723http://purl.uniprot.org/core/author"Tanabe T."xsd:string
http://purl.uniprot.org/citations/1714723http://purl.uniprot.org/core/author"Tanabe T."xsd:string
http://purl.uniprot.org/citations/1714723http://purl.uniprot.org/core/author"Yokoyama C."xsd:string
http://purl.uniprot.org/citations/1714723http://purl.uniprot.org/core/author"Yokoyama C."xsd:string
http://purl.uniprot.org/citations/1714723http://purl.uniprot.org/core/author"Miyata A."xsd:string
http://purl.uniprot.org/citations/1714723http://purl.uniprot.org/core/author"Miyata A."xsd:string
http://purl.uniprot.org/citations/1714723http://purl.uniprot.org/core/author"Ullrich V."xsd:string
http://purl.uniprot.org/citations/1714723http://purl.uniprot.org/core/author"Ullrich V."xsd:string
http://purl.uniprot.org/citations/1714723http://purl.uniprot.org/core/date"1991"xsd:gYear
http://purl.uniprot.org/citations/1714723http://purl.uniprot.org/core/date"1991"xsd:gYear
http://purl.uniprot.org/citations/1714723http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/1714723http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/1714723http://purl.uniprot.org/core/pages"1479-1484"xsd:string
http://purl.uniprot.org/citations/1714723http://purl.uniprot.org/core/pages"1479-1484"xsd:string
http://purl.uniprot.org/citations/1714723http://purl.uniprot.org/core/title"Molecular cloning of human platelet thromboxane A synthase."xsd:string
http://purl.uniprot.org/citations/1714723http://purl.uniprot.org/core/title"Molecular cloning of human platelet thromboxane A synthase."xsd:string
http://purl.uniprot.org/citations/1714723http://purl.uniprot.org/core/volume"178"xsd:string
http://purl.uniprot.org/citations/1714723http://purl.uniprot.org/core/volume"178"xsd:string