http://purl.uniprot.org/citations/17289999 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/17289999 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/17289999 | http://www.w3.org/2000/01/rdf-schema#comment | "A central issue in the regulation of apoptosis by the Bcl-2 family is whether its BH3-only members initiate apoptosis by directly binding to the essential cell-death mediators Bax and Bak, or whether they can act indirectly, by engaging their pro-survival Bcl-2-like relatives. Contrary to the direct-activation model, we show that Bax and Bak can mediate apoptosis without discernable association with the putative BH3-only activators (Bim, Bid, and Puma), even in cells with no Bim or Bid and reduced Puma. Our results indicate that BH3-only proteins induce apoptosis at least primarily by engaging the multiple pro-survival relatives guarding Bax and Bak."xsd:string |
http://purl.uniprot.org/citations/17289999 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1133289"xsd:string |
http://purl.uniprot.org/citations/17289999 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1133289"xsd:string |
http://purl.uniprot.org/citations/17289999 | http://purl.uniprot.org/core/author | "Chen L."xsd:string |
http://purl.uniprot.org/citations/17289999 | http://purl.uniprot.org/core/author | "Chen L."xsd:string |
http://purl.uniprot.org/citations/17289999 | http://purl.uniprot.org/core/author | "Czabotar P.E."xsd:string |
http://purl.uniprot.org/citations/17289999 | http://purl.uniprot.org/core/author | "Czabotar P.E."xsd:string |
http://purl.uniprot.org/citations/17289999 | http://purl.uniprot.org/core/author | "Adams J.M."xsd:string |
http://purl.uniprot.org/citations/17289999 | http://purl.uniprot.org/core/author | "Adams J.M."xsd:string |
http://purl.uniprot.org/citations/17289999 | http://purl.uniprot.org/core/author | "Huang D.C."xsd:string |
http://purl.uniprot.org/citations/17289999 | http://purl.uniprot.org/core/author | "Huang D.C."xsd:string |
http://purl.uniprot.org/citations/17289999 | http://purl.uniprot.org/core/author | "Fletcher J.I."xsd:string |
http://purl.uniprot.org/citations/17289999 | http://purl.uniprot.org/core/author | "Fletcher J.I."xsd:string |
http://purl.uniprot.org/citations/17289999 | http://purl.uniprot.org/core/author | "Willis S.N."xsd:string |
http://purl.uniprot.org/citations/17289999 | http://purl.uniprot.org/core/author | "Willis S.N."xsd:string |
http://purl.uniprot.org/citations/17289999 | http://purl.uniprot.org/core/author | "Fairlie W.D."xsd:string |
http://purl.uniprot.org/citations/17289999 | http://purl.uniprot.org/core/author | "Fairlie W.D."xsd:string |
http://purl.uniprot.org/citations/17289999 | http://purl.uniprot.org/core/author | "Bouillet P."xsd:string |
http://purl.uniprot.org/citations/17289999 | http://purl.uniprot.org/core/author | "Bouillet P."xsd:string |
http://purl.uniprot.org/citations/17289999 | http://purl.uniprot.org/core/author | "Lee E.F."xsd:string |
http://purl.uniprot.org/citations/17289999 | http://purl.uniprot.org/core/author | "Lee E.F."xsd:string |
http://purl.uniprot.org/citations/17289999 | http://purl.uniprot.org/core/author | "Strasser A."xsd:string |
http://purl.uniprot.org/citations/17289999 | http://purl.uniprot.org/core/author | "Strasser A."xsd:string |