| http://purl.uniprot.org/citations/17356920 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17356920 | http://www.w3.org/2000/01/rdf-schema#comment | "The Wnt/beta-catenin pathway has been proposed as promoting intestinal stem cell division. Wnt ligands activate cytoplasmic beta-catenin and increase nuclear translocation of beta-catenin that binds to the Tcf-4 transcription factor. The aim of this study was to investigate beta-catenin expression in the stem cell region of crypts during intestinal growth in rats. Litters of DAxPVG/c rats were humanely killed at 7, 14, 21, 35, and 72 days of life. beta-Catenin and Tcf-4 were quantified by immunoperoxidase staining and image analysis with cumulative signal analysis. Cytoplasmic and nuclear expression of beta-catenin peaked nearly 2-fold at day 14 (versus day 7) of life in the stem cell region of intestinal crypts. Tcf-4 nuclear expression peaked earlier at 7 days and was lower thereafter with age. We conclude that the Wnt/beta-catenin pathway is activated in the stem cell region of intestinal crypts during growth of the small intestine."xsd:string |
| http://purl.uniprot.org/citations/17356920 | http://purl.org/dc/terms/identifier | "doi:10.1007/s10620-006-9200-7"xsd:string |
| http://purl.uniprot.org/citations/17356920 | http://purl.uniprot.org/core/author | "Cummins A.G."xsd:string |
| http://purl.uniprot.org/citations/17356920 | http://purl.uniprot.org/core/author | "Camac K.S."xsd:string |
| http://purl.uniprot.org/citations/17356920 | http://purl.uniprot.org/core/author | "Thompson F.M."xsd:string |
| http://purl.uniprot.org/citations/17356920 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17356920 | http://purl.uniprot.org/core/name | "Dig Dis Sci"xsd:string |
| http://purl.uniprot.org/citations/17356920 | http://purl.uniprot.org/core/pages | "1242-1246"xsd:string |
| http://purl.uniprot.org/citations/17356920 | http://purl.uniprot.org/core/title | "Activation of beta-catenin in the stem cell region of crypts during growth of the small intestine in infant rats."xsd:string |
| http://purl.uniprot.org/citations/17356920 | http://purl.uniprot.org/core/volume | "52"xsd:string |
| http://purl.uniprot.org/citations/17356920 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17356920 |
| http://purl.uniprot.org/citations/17356920 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17356920 |
| http://purl.uniprot.org/uniprot/Q9WU82#attribution-64E73CEB84A3E1A226FD52232F32DDE6 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/17356920 |
| http://purl.uniprot.org/uniprot/#_A0A0G2JT93-mappedCitation-17356920 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17356920 |
| http://purl.uniprot.org/uniprot/#_A0A8I6GKV3-mappedCitation-17356920 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17356920 |
| http://purl.uniprot.org/uniprot/#_B6DMG1-mappedCitation-17356920 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17356920 |
| http://purl.uniprot.org/uniprot/#_Q9WU82-mappedCitation-17356920 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17356920 |
| http://purl.uniprot.org/uniprot/A0A0G2JT93 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17356920 |
| http://purl.uniprot.org/uniprot/Q9WU82 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17356920 |
| http://purl.uniprot.org/uniprot/B6DMG1 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17356920 |
| http://purl.uniprot.org/uniprot/A0A8I6GKV3 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17356920 |