http://purl.uniprot.org/citations/18201566 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/18201566 | http://www.w3.org/2000/01/rdf-schema#comment | "Alpha-dystroglycan (alpha-DG) plays a crucial role in maintaining the stability of muscle cell membrane. Although it has been shown that the N-terminal domain of alpha-DG (alpha-DG-N) is cleaved by a proprotein convertase, its physiological significance remains unclear. We show here that native alpha-DG-N is secreted by a wide variety of cultured cells into the culture media. The secreted alpha-DG-N was both N- and O-glycosylated. Finally, a small amount of alpha-DG-N was detectable in the normal human serum. These observations indicate that the cleavage of alpha-DG-N is a widespread event and suggest that the secreted alpha-DG-N might be transported via systemic circulation in vivo."xsd:string |
http://purl.uniprot.org/citations/18201566 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2008.01.006"xsd:string |
http://purl.uniprot.org/citations/18201566 | http://purl.uniprot.org/core/author | "Matsumura K."xsd:string |
http://purl.uniprot.org/citations/18201566 | http://purl.uniprot.org/core/author | "Nakamura A."xsd:string |
http://purl.uniprot.org/citations/18201566 | http://purl.uniprot.org/core/author | "Shimizu T."xsd:string |
http://purl.uniprot.org/citations/18201566 | http://purl.uniprot.org/core/author | "Saito F."xsd:string |
http://purl.uniprot.org/citations/18201566 | http://purl.uniprot.org/core/author | "Saito-Arai Y."xsd:string |
http://purl.uniprot.org/citations/18201566 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
http://purl.uniprot.org/citations/18201566 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
http://purl.uniprot.org/citations/18201566 | http://purl.uniprot.org/core/pages | "439-444"xsd:string |
http://purl.uniprot.org/citations/18201566 | http://purl.uniprot.org/core/title | "Processing and secretion of the N-terminal domain of alpha-dystroglycan in cell culture media."xsd:string |
http://purl.uniprot.org/citations/18201566 | http://purl.uniprot.org/core/volume | "582"xsd:string |
http://purl.uniprot.org/citations/18201566 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18201566 |
http://purl.uniprot.org/citations/18201566 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/18201566 |
http://purl.uniprot.org/uniprot/Q14118#attribution-B13CFF964271893F20D27E0C37BB5FF3 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/18201566 |