| http://purl.uniprot.org/citations/18314226 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/18314226 | http://www.w3.org/2000/01/rdf-schema#comment | "Semenogelin I (SgI) is one of the most abundant proteins in human seminal plasma. SgI plays a key role in sperm coagulation and spermatozoon immobilization. In addition, SgI and/or its proteolytic fragments are involved in regulating spermatozoon motility, capacitation and inhibin-like activity. However, little is known about the antibacterial activity of SgI-derived peptides. By a combination of ion-exchange, gel filtration and high-performance liquid chromatography, peptides from liquefied human seminal plasma from 40 healthy donors were isolated and characterized. N-terminal amino-acid sequencing and fast atom bombardment mass spectrometry revealed that four isolated peptides were SgI-derived, namely SgI-29 (85-113), SgI-46 (85-130), SgI-47 (85-131) and SgI-52 (85-136). Interestingly, SgI-29, SgI-46 and SgI-47 are newly identified SgI-derived peptides. Antimicrobial activity assay results indicated that synthesized SgI-29 had strong antibacterial activity toward various bacterial strains. Our results indicate that SgI can be digested into small fragments like newly identified SgI-29, SgI-46 and SgI-47 and may have diversified functions."xsd:string |
| http://purl.uniprot.org/citations/18314226 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.peptides.2008.01.009"xsd:string |
| http://purl.uniprot.org/citations/18314226 | http://purl.uniprot.org/core/author | "Li H."xsd:string |
| http://purl.uniprot.org/citations/18314226 | http://purl.uniprot.org/core/author | "Lee W.H."xsd:string |
| http://purl.uniprot.org/citations/18314226 | http://purl.uniprot.org/core/author | "Zhang Y."xsd:string |
| http://purl.uniprot.org/citations/18314226 | http://purl.uniprot.org/core/author | "Zhao H."xsd:string |
| http://purl.uniprot.org/citations/18314226 | http://purl.uniprot.org/core/author | "Shen J.H."xsd:string |
| http://purl.uniprot.org/citations/18314226 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
| http://purl.uniprot.org/citations/18314226 | http://purl.uniprot.org/core/name | "Peptides"xsd:string |
| http://purl.uniprot.org/citations/18314226 | http://purl.uniprot.org/core/pages | "505-511"xsd:string |
| http://purl.uniprot.org/citations/18314226 | http://purl.uniprot.org/core/title | "Identification of novel semenogelin I-derived antimicrobial peptide from liquefied human seminal plasma."xsd:string |
| http://purl.uniprot.org/citations/18314226 | http://purl.uniprot.org/core/volume | "29"xsd:string |
| http://purl.uniprot.org/citations/18314226 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18314226 |
| http://purl.uniprot.org/citations/18314226 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/18314226 |
| http://purl.uniprot.org/uniprot/P04279#attribution-FB914FFAC3B2387DED0D65A93CF092B3 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/18314226 |