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http://purl.uniprot.org/citations/18387192http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/18387192http://www.w3.org/2000/01/rdf-schema#comment"Protein cleavage is a central event in many regulated biological processes. We describe a system for detecting intracellular proteolysis based on non-conventional secretion of Gaussia luciferase (GLUC). GLUC exits the cell without benefit of a secretory leader peptide, but can be anchored in the cell by fusion to beta-actin. By including protease cleavage sites between GLUC and beta-actin, proteolytic cleavage can be detected. Using this assay, we have identified regulators of autophagy, apoptosis and beta-actin cleavage."xsd:string
http://purl.uniprot.org/citations/18387192http://purl.org/dc/terms/identifier"doi:10.1186/gb-2008-9-4-r64"xsd:string
http://purl.uniprot.org/citations/18387192http://purl.uniprot.org/core/author"Sun Z."xsd:string
http://purl.uniprot.org/citations/18387192http://purl.uniprot.org/core/author"Seed B."xsd:string
http://purl.uniprot.org/citations/18387192http://purl.uniprot.org/core/author"He W.W."xsd:string
http://purl.uniprot.org/citations/18387192http://purl.uniprot.org/core/author"Ketteler R."xsd:string
http://purl.uniprot.org/citations/18387192http://purl.uniprot.org/core/author"Kovacs K.F."xsd:string
http://purl.uniprot.org/citations/18387192http://purl.uniprot.org/core/date"2008"xsd:gYear
http://purl.uniprot.org/citations/18387192http://purl.uniprot.org/core/name"Genome Biol"xsd:string
http://purl.uniprot.org/citations/18387192http://purl.uniprot.org/core/pages"R64"xsd:string
http://purl.uniprot.org/citations/18387192http://purl.uniprot.org/core/title"A pathway sensor for genome-wide screens of intracellular proteolytic cleavage."xsd:string
http://purl.uniprot.org/citations/18387192http://purl.uniprot.org/core/volume"9"xsd:string
http://purl.uniprot.org/citations/18387192http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/18387192
http://purl.uniprot.org/citations/18387192http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/18387192
http://purl.uniprot.org/uniprot/P31749#attribution-A42E56E5F9C8EB700C0AB94FD142D1D9http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/18387192
http://purl.uniprot.org/uniprot/Q9Y4P1#attribution-9478782512440D614F9E437AE99B73BFhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/18387192
http://purl.uniprot.org/uniprot/Q12797#attribution-9478782512440D614F9E437AE99B73BFhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/18387192
http://purl.uniprot.org/uniprot/Q92934#attribution-9478782512440D614F9E437AE99B73BFhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/18387192
http://purl.uniprot.org/uniprot/Q16611#attribution-9478782512440D614F9E437AE99B73BFhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/18387192
http://purl.uniprot.org/uniprot/Q14790#attribution-9478782512440D614F9E437AE99B73BFhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/18387192
http://purl.uniprot.org/uniprot/Q96F07#attribution-9478782512440D614F9E437AE99B73BFhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/18387192
http://purl.uniprot.org/uniprot/Q13158#attribution-9478782512440D614F9E437AE99B73BFhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/18387192
http://purl.uniprot.org/uniprot/P83110#attribution-9478782512440D614F9E437AE99B73BFhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/18387192
http://purl.uniprot.org/uniprot/P83105#attribution-9478782512440D614F9E437AE99B73BFhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/18387192