http://purl.uniprot.org/citations/18387192 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/18387192 | http://www.w3.org/2000/01/rdf-schema#comment | "Protein cleavage is a central event in many regulated biological processes. We describe a system for detecting intracellular proteolysis based on non-conventional secretion of Gaussia luciferase (GLUC). GLUC exits the cell without benefit of a secretory leader peptide, but can be anchored in the cell by fusion to beta-actin. By including protease cleavage sites between GLUC and beta-actin, proteolytic cleavage can be detected. Using this assay, we have identified regulators of autophagy, apoptosis and beta-actin cleavage."xsd:string |
http://purl.uniprot.org/citations/18387192 | http://purl.org/dc/terms/identifier | "doi:10.1186/gb-2008-9-4-r64"xsd:string |
http://purl.uniprot.org/citations/18387192 | http://purl.uniprot.org/core/author | "Sun Z."xsd:string |
http://purl.uniprot.org/citations/18387192 | http://purl.uniprot.org/core/author | "Seed B."xsd:string |
http://purl.uniprot.org/citations/18387192 | http://purl.uniprot.org/core/author | "He W.W."xsd:string |
http://purl.uniprot.org/citations/18387192 | http://purl.uniprot.org/core/author | "Ketteler R."xsd:string |
http://purl.uniprot.org/citations/18387192 | http://purl.uniprot.org/core/author | "Kovacs K.F."xsd:string |
http://purl.uniprot.org/citations/18387192 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
http://purl.uniprot.org/citations/18387192 | http://purl.uniprot.org/core/name | "Genome Biol"xsd:string |
http://purl.uniprot.org/citations/18387192 | http://purl.uniprot.org/core/pages | "R64"xsd:string |
http://purl.uniprot.org/citations/18387192 | http://purl.uniprot.org/core/title | "A pathway sensor for genome-wide screens of intracellular proteolytic cleavage."xsd:string |
http://purl.uniprot.org/citations/18387192 | http://purl.uniprot.org/core/volume | "9"xsd:string |
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http://purl.uniprot.org/uniprot/Q14790#attribution-9478782512440D614F9E437AE99B73BF | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/18387192 |
http://purl.uniprot.org/uniprot/Q96F07#attribution-9478782512440D614F9E437AE99B73BF | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/18387192 |
http://purl.uniprot.org/uniprot/Q13158#attribution-9478782512440D614F9E437AE99B73BF | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/18387192 |
http://purl.uniprot.org/uniprot/P83110#attribution-9478782512440D614F9E437AE99B73BF | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/18387192 |
http://purl.uniprot.org/uniprot/P83105#attribution-9478782512440D614F9E437AE99B73BF | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/18387192 |