http://purl.uniprot.org/citations/18548008 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/18548008 | http://www.w3.org/2000/01/rdf-schema#comment | "B-Myb is one member of the vertebrate Myb family of transcription factors and is ubiquitously expressed. B-Myb activates transcription of a group of genes required for the G2/M cell cycle transition by forming the dREAM/Myb-MuvB-like complex, which was originally identified in Drosophila. Mutants of zebrafish B-myb and Drosophila myb exhibit defects in cell cycle progression and genome instability. Although the genome instability caused by a loss of B-Myb has been speculated to be due to abnormal cell cycle progression, the precise mechanism remains unknown. Here, we have purified a B-Myb complex containing clathrin and filamin (Myb-Clafi complex). This complex is required for normal localization of clathrin at the mitotic spindle, which was previously reported to stabilize kinetochore fibres. The Myb-Clafi complex is not tightly associated with the mitotic spindles, suggesting that this complex ferries clathrin to the mitotic spindles. Thus, identification of the Myb-Clafi complex reveals a previously unrecognized function of B-Myb that may contribute to its role in chromosome stability, possibly, tumour suppression."xsd:string |
http://purl.uniprot.org/citations/18548008 | http://purl.org/dc/terms/identifier | "doi:10.1038/emboj.2008.118"xsd:string |
http://purl.uniprot.org/citations/18548008 | http://purl.uniprot.org/core/author | "Ishii S."xsd:string |
http://purl.uniprot.org/citations/18548008 | http://purl.uniprot.org/core/author | "Tanaka Y."xsd:string |
http://purl.uniprot.org/citations/18548008 | http://purl.uniprot.org/core/author | "Nomura T."xsd:string |
http://purl.uniprot.org/citations/18548008 | http://purl.uniprot.org/core/author | "Yamauchi T."xsd:string |
http://purl.uniprot.org/citations/18548008 | http://purl.uniprot.org/core/author | "Yonemura S."xsd:string |
http://purl.uniprot.org/citations/18548008 | http://purl.uniprot.org/core/author | "Shinagawa T."xsd:string |
http://purl.uniprot.org/citations/18548008 | http://purl.uniprot.org/core/author | "Ishidao T."xsd:string |
http://purl.uniprot.org/citations/18548008 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
http://purl.uniprot.org/citations/18548008 | http://purl.uniprot.org/core/name | "EMBO J"xsd:string |
http://purl.uniprot.org/citations/18548008 | http://purl.uniprot.org/core/pages | "1852-1862"xsd:string |
http://purl.uniprot.org/citations/18548008 | http://purl.uniprot.org/core/title | "A B-Myb complex containing clathrin and filamin is required for mitotic spindle function."xsd:string |
http://purl.uniprot.org/citations/18548008 | http://purl.uniprot.org/core/volume | "27"xsd:string |
http://purl.uniprot.org/citations/18548008 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/18548008 |
http://purl.uniprot.org/citations/18548008 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/18548008 |
http://purl.uniprot.org/uniprot/Q68FD5#attribution-B10DD83D50442D2F9B1A389989C0C534 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/18548008 |
http://purl.uniprot.org/uniprot/Q8BTM8#attribution-B10DD83D50442D2F9B1A389989C0C534 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/18548008 |
http://purl.uniprot.org/uniprot/P21333#attribution-B11E86B89169A109425F8D87447944CF | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/18548008 |
http://purl.uniprot.org/uniprot/P48972#attribution-B11E86B89169A109425F8D87447944CF | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/18548008 |
http://purl.uniprot.org/uniprot/Q49AL0#attribution-B11E86B89169A109425F8D87447944CF | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/18548008 |
http://purl.uniprot.org/uniprot/#_A2A5P3-mappedCitation-18548008 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18548008 |
http://purl.uniprot.org/uniprot/#_A0A668KLG7-mappedCitation-18548008 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18548008 |
http://purl.uniprot.org/uniprot/#_A2VCP8-mappedCitation-18548008 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/18548008 |