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http://purl.uniprot.org/citations/18756329http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/18756329http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/18756329http://www.w3.org/2000/01/rdf-schema#comment"rsb-66 is a novel gene from a suppression subtracted hybridization (SSH) library of round spermatid-specific cDNAs against those of primary spermatocytes. It was found to be specifically expressed in round spermatids. To explore the function of RSB-66, a yeast two-hybrid system was used to screen for potential interacting partners in a human testis cDNA library. HSD45, also known as INCA1 (inhibitor of Cdk interacting with cyclin A1), was identified as one of the positive clones. The interaction between RSB-66 and INCA1 was demonstrated to occur by GST pull down and coimmunoprecipitation. Using immunofluorescence, RSB-66 was found to be specifically expressed in round spermatids, mainly in the cytoplasm. When being transfected into HeLa cells, RSB-66 and INCA1 were found to be co-localized principally in the cytoplasm. The alpha helix in the RSB-66 C terminal and two amino acid residues (tyr117 and his119) appear to be crucial for its function."xsd:string
http://purl.uniprot.org/citations/18756329http://purl.org/dc/terms/identifier"doi:10.1139/o08-072"xsd:string
http://purl.uniprot.org/citations/18756329http://purl.org/dc/terms/identifier"doi:10.1139/o08-072"xsd:string
http://purl.uniprot.org/citations/18756329http://purl.uniprot.org/core/author"Chen X."xsd:string
http://purl.uniprot.org/citations/18756329http://purl.uniprot.org/core/author"Chen X."xsd:string
http://purl.uniprot.org/citations/18756329http://purl.uniprot.org/core/author"Wang L."xsd:string
http://purl.uniprot.org/citations/18756329http://purl.uniprot.org/core/author"Wang L."xsd:string
http://purl.uniprot.org/citations/18756329http://purl.uniprot.org/core/author"Yang M."xsd:string
http://purl.uniprot.org/citations/18756329http://purl.uniprot.org/core/author"Yang M."xsd:string
http://purl.uniprot.org/citations/18756329http://purl.uniprot.org/core/author"Hu T."xsd:string
http://purl.uniprot.org/citations/18756329http://purl.uniprot.org/core/author"Hu T."xsd:string
http://purl.uniprot.org/citations/18756329http://purl.uniprot.org/core/author"Liang G."xsd:string
http://purl.uniprot.org/citations/18756329http://purl.uniprot.org/core/author"Liang G."xsd:string
http://purl.uniprot.org/citations/18756329http://purl.uniprot.org/core/author"Miao S."xsd:string
http://purl.uniprot.org/citations/18756329http://purl.uniprot.org/core/author"Miao S."xsd:string
http://purl.uniprot.org/citations/18756329http://purl.uniprot.org/core/author"Koide S.S."xsd:string
http://purl.uniprot.org/citations/18756329http://purl.uniprot.org/core/author"Koide S.S."xsd:string
http://purl.uniprot.org/citations/18756329http://purl.uniprot.org/core/author"Zong S."xsd:string
http://purl.uniprot.org/citations/18756329http://purl.uniprot.org/core/author"Zong S."xsd:string
http://purl.uniprot.org/citations/18756329http://purl.uniprot.org/core/date"2008"xsd:gYear
http://purl.uniprot.org/citations/18756329http://purl.uniprot.org/core/date"2008"xsd:gYear
http://purl.uniprot.org/citations/18756329http://purl.uniprot.org/core/name"Biochem. Cell Biol."xsd:string
http://purl.uniprot.org/citations/18756329http://purl.uniprot.org/core/name"Biochem. Cell Biol."xsd:string