| http://purl.uniprot.org/citations/19039327 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19039327 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19039327 | http://www.w3.org/2000/01/rdf-schema#comment | "Steroid receptor coactivators (SRCs) exert profound effects on animal development and physiology. Genetic ablation experiments indicate that various SRC proteins might have differential physiological roles; however, clear evidence of functional specificity has not yet been shown at the molecular level. Here we report the identification of a new SRC1 interacting protein, glutamate-rich coactivator interacting with SRC1 (GAS), which contains a central glutamate-rich region and has transactivation activity. Interestingly, GAS interacts only with SRC1, and not with glucocorticoid receptor interacting protein 1 (GRIP1) or amplified in breast cancer 1 (AIB1), the other two members of the SRC family. It interacts with oestrogen receptor-alpha (ERalpha) and participates in both oestrogen receptor-regulated gene transcription and oestrogen-stimulated G1/S cell-cycle transition. Our data thus indicate that GAS is a new transcription cofactor and that different SRCs are associated with distinct secondary cofactors."xsd:string |
| http://purl.uniprot.org/citations/19039327 | http://purl.org/dc/terms/identifier | "doi:10.1038/embor.2008.223"xsd:string |
| http://purl.uniprot.org/citations/19039327 | http://purl.org/dc/terms/identifier | "doi:10.1038/embor.2008.223"xsd:string |
| http://purl.uniprot.org/citations/19039327 | http://purl.uniprot.org/core/author | "Shang Y."xsd:string |
| http://purl.uniprot.org/citations/19039327 | http://purl.uniprot.org/core/author | "Shang Y."xsd:string |
| http://purl.uniprot.org/citations/19039327 | http://purl.uniprot.org/core/author | "Zhang Y."xsd:string |
| http://purl.uniprot.org/citations/19039327 | http://purl.uniprot.org/core/author | "Zhang Y."xsd:string |
| http://purl.uniprot.org/citations/19039327 | http://purl.uniprot.org/core/author | "Zhang H."xsd:string |
| http://purl.uniprot.org/citations/19039327 | http://purl.uniprot.org/core/author | "Zhang H."xsd:string |
| http://purl.uniprot.org/citations/19039327 | http://purl.uniprot.org/core/author | "Zhang Y.'"xsd:string |
| http://purl.uniprot.org/citations/19039327 | http://purl.uniprot.org/core/author | "Zhang Y.'"xsd:string |
| http://purl.uniprot.org/citations/19039327 | http://purl.uniprot.org/core/author | "Liang J."xsd:string |
| http://purl.uniprot.org/citations/19039327 | http://purl.uniprot.org/core/author | "Liang J."xsd:string |
| http://purl.uniprot.org/citations/19039327 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19039327 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19039327 | http://purl.uniprot.org/core/name | "EMBO Rep."xsd:string |
| http://purl.uniprot.org/citations/19039327 | http://purl.uniprot.org/core/name | "EMBO Rep."xsd:string |
| http://purl.uniprot.org/citations/19039327 | http://purl.uniprot.org/core/pages | "51-57"xsd:string |
| http://purl.uniprot.org/citations/19039327 | http://purl.uniprot.org/core/pages | "51-57"xsd:string |
| http://purl.uniprot.org/citations/19039327 | http://purl.uniprot.org/core/title | "GAS, a new glutamate-rich protein, interacts differentially with SRCs and is involved in oestrogen receptor function."xsd:string |
| http://purl.uniprot.org/citations/19039327 | http://purl.uniprot.org/core/title | "GAS, a new glutamate-rich protein, interacts differentially with SRCs and is involved in oestrogen receptor function."xsd:string |
| http://purl.uniprot.org/citations/19039327 | http://purl.uniprot.org/core/volume | "10"xsd:string |
| http://purl.uniprot.org/citations/19039327 | http://purl.uniprot.org/core/volume | "10"xsd:string |