RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/19097687http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19097687http://www.w3.org/2000/01/rdf-schema#comment"We have previously reported that Bcl-w enhances the invasiveness of gastric cancer cells by inducing MMP-2 expression via phosphoinositide 3-kinase (PI3K), Akt and Sp1. This study demonstrates that Bcl-w additionally induces uPA expression and FAK activation. Analyses of the hierarchical relationship and functions of these components showed that the PI3K-Akt-Sp1 pathway also mediates the induction of uPA, and that both uPA and MMP-2 contribute to Bcl-w-induced invasion via the stimulation of the FAK-dependent migratory pathway. These findings significantly advance our understandings of the Bcl-w-induced signaling processes that results in the migration and invasion of cancer cells."xsd:string
http://purl.uniprot.org/citations/19097687http://purl.org/dc/terms/identifier"doi:10.1016/j.canlet.2008.11.022"xsd:string
http://purl.uniprot.org/citations/19097687http://purl.uniprot.org/core/author"Lee S.B."xsd:string
http://purl.uniprot.org/citations/19097687http://purl.uniprot.org/core/author"Yoon S.H."xsd:string
http://purl.uniprot.org/citations/19097687http://purl.uniprot.org/core/author"Um H.D."xsd:string
http://purl.uniprot.org/citations/19097687http://purl.uniprot.org/core/author"Park J.K."xsd:string
http://purl.uniprot.org/citations/19097687http://purl.uniprot.org/core/author"Bae I.H."xsd:string
http://purl.uniprot.org/citations/19097687http://purl.uniprot.org/core/author"Ho J.N."xsd:string
http://purl.uniprot.org/citations/19097687http://purl.uniprot.org/core/date"2009"xsd:gYear
http://purl.uniprot.org/citations/19097687http://purl.uniprot.org/core/name"Cancer Lett"xsd:string
http://purl.uniprot.org/citations/19097687http://purl.uniprot.org/core/pages"22-28"xsd:string
http://purl.uniprot.org/citations/19097687http://purl.uniprot.org/core/title"Signaling components involved in Bcl-w-induced migration of gastric cancer cells."xsd:string
http://purl.uniprot.org/citations/19097687http://purl.uniprot.org/core/volume"277"xsd:string
http://purl.uniprot.org/citations/19097687http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/19097687
http://purl.uniprot.org/citations/19097687http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/19097687
http://purl.uniprot.org/uniprot/#_Q92843-mappedCitation-19097687http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19097687
http://purl.uniprot.org/uniprot/Q92843http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/19097687