| http://purl.uniprot.org/citations/19264983 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19264983 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19264983 | http://www.w3.org/2000/01/rdf-schema#comment | "Patten recognition receptors, which recognize pathogens or components of injured cells (danger), trigger activation of the innate immune system. Whether and how the host distinguishes between danger-versus pathogen-associated molecular patterns remains unresolved. We report that CD24-deficient mice exhibit increased susceptibility to danger-but not pathogen-associated molecular patterns. CD24 associates with high mobility group box 1, heat shock protein 70, and heat shock protein 90; negatively regulates their stimulatory activity; and inhibits nuclear factor kappaB (NF-kappaB) activation. This occurs at least in part through CD24 association with Siglec-10 in humans or Siglec-G in mice. Our results reveal that the CD24-Siglec G pathway protects the host against a lethal response to pathological cell death and discriminates danger-versus pathogen-associated molecular patterns."xsd:string |
| http://purl.uniprot.org/citations/19264983 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1168988"xsd:string |
| http://purl.uniprot.org/citations/19264983 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1168988"xsd:string |
| http://purl.uniprot.org/citations/19264983 | http://purl.uniprot.org/core/author | "Liu Y."xsd:string |
| http://purl.uniprot.org/citations/19264983 | http://purl.uniprot.org/core/author | "Liu Y."xsd:string |
| http://purl.uniprot.org/citations/19264983 | http://purl.uniprot.org/core/author | "Zheng P."xsd:string |
| http://purl.uniprot.org/citations/19264983 | http://purl.uniprot.org/core/author | "Zheng P."xsd:string |
| http://purl.uniprot.org/citations/19264983 | http://purl.uniprot.org/core/author | "Tang J."xsd:string |
| http://purl.uniprot.org/citations/19264983 | http://purl.uniprot.org/core/author | "Tang J."xsd:string |
| http://purl.uniprot.org/citations/19264983 | http://purl.uniprot.org/core/author | "Chen G.Y."xsd:string |
| http://purl.uniprot.org/citations/19264983 | http://purl.uniprot.org/core/author | "Chen G.Y."xsd:string |
| http://purl.uniprot.org/citations/19264983 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19264983 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19264983 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/19264983 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/19264983 | http://purl.uniprot.org/core/pages | "1722-1725"xsd:string |
| http://purl.uniprot.org/citations/19264983 | http://purl.uniprot.org/core/pages | "1722-1725"xsd:string |
| http://purl.uniprot.org/citations/19264983 | http://purl.uniprot.org/core/title | "CD24 and Siglec-10 selectively repress tissue damage-induced immune responses."xsd:string |
| http://purl.uniprot.org/citations/19264983 | http://purl.uniprot.org/core/title | "CD24 and Siglec-10 selectively repress tissue damage-induced immune responses."xsd:string |
| http://purl.uniprot.org/citations/19264983 | http://purl.uniprot.org/core/volume | "323"xsd:string |
| http://purl.uniprot.org/citations/19264983 | http://purl.uniprot.org/core/volume | "323"xsd:string |
| http://purl.uniprot.org/citations/19264983 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19264983 |
| http://purl.uniprot.org/citations/19264983 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19264983 |