http://purl.uniprot.org/citations/19822147 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/19822147 | http://www.w3.org/2000/01/rdf-schema#comment | "Manganese superoxide dismutase (MnSOD) is vital to the protection of mitochondria and cells against oxidative stress. Earlier, we demonstrated that catalytically active homo-tetramer of MnSOD can be stabilized by oxidative cross-linking. Here we report that this effect may be translated into increased radioresistance of mouse embryonic cells (MECs) by pre-exposure to oxidative stress. Pre-treatment of MECs with antimycin A, rotenone or H(2)O(2) increased their survival after irradiation. Using MnSOD siRNA, we show that MECs with decreased MnSOD levels displayed a lowered ability to preconditioning. Thus oxidative preconditioning may be used for targeted regulation of MnSOD."xsd:string |
http://purl.uniprot.org/citations/19822147 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2009.10.013"xsd:string |
http://purl.uniprot.org/citations/19822147 | http://purl.uniprot.org/core/author | "Jiang J."xsd:string |
http://purl.uniprot.org/citations/19822147 | http://purl.uniprot.org/core/author | "Bayir H."xsd:string |
http://purl.uniprot.org/citations/19822147 | http://purl.uniprot.org/core/author | "Greenberger J.S."xsd:string |
http://purl.uniprot.org/citations/19822147 | http://purl.uniprot.org/core/author | "Kagan V.E."xsd:string |
http://purl.uniprot.org/citations/19822147 | http://purl.uniprot.org/core/author | "Rafikov R."xsd:string |
http://purl.uniprot.org/citations/19822147 | http://purl.uniprot.org/core/author | "Belikova N.A."xsd:string |
http://purl.uniprot.org/citations/19822147 | http://purl.uniprot.org/core/author | "Glumac A."xsd:string |
http://purl.uniprot.org/citations/19822147 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
http://purl.uniprot.org/citations/19822147 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
http://purl.uniprot.org/citations/19822147 | http://purl.uniprot.org/core/pages | "3437-3442"xsd:string |
http://purl.uniprot.org/citations/19822147 | http://purl.uniprot.org/core/title | "Radioprotection by short-term oxidative preconditioning: role of manganese superoxide dismutase."xsd:string |
http://purl.uniprot.org/citations/19822147 | http://purl.uniprot.org/core/volume | "583"xsd:string |
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