| http://purl.uniprot.org/citations/2001840 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2001840 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2001840 | http://www.w3.org/2000/01/rdf-schema#comment | "The Wnt gene family encodes a group of cysteine-rich proteins implicated in intercellular signaling during several stages of vertebrate development. This family includes Wnt-1 and Wnt-3, both discovered as activated oncogenes in mouse mammary tumors. Here we describe the molecular cloning of an additional member of the Wnt family, called Wnt-3A, and the spatial and temporal expression pattern of this gene as well as that of its close relative Wnt-3. The putative amino acid sequences of both proteins are almost 90% identical, but in situ hybridization to mouse embryo sections showed highly restricted patterns of expression of Wnt-3 and Wnt-3A, largely in separate areas in the developing nervous system. In the spinal cord Wnt-3 was expressed at low levels in the alar laminae and in the ventral horns, whereas Wnt-3A expression was confined to the roof plate. In the developing brain Wnt-3 was expressed broadly across the dorsal portion of the neural tube with a rostral boundary of expression at the diencephalon. In contrast, Wnt-3A was expressed in a narrow region very close to the midline; expression extended into the bifurcating telencephalon, in a highly localized fashion. Both Wnt-3 and Wnt-3A were expressed in the ectoderm, and Wnt-3A was also expressed in the periumbilical mesenchyme. Characteristic expression patterns of these two closely related genes suggest that Wnt-3 and Wnt-3A play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube."xsd:string |
| http://purl.uniprot.org/citations/2001840 | http://purl.org/dc/terms/identifier | "doi:10.1101/gad.5.3.381"xsd:string |
| http://purl.uniprot.org/citations/2001840 | http://purl.org/dc/terms/identifier | "doi:10.1101/gad.5.3.381"xsd:string |
| http://purl.uniprot.org/citations/2001840 | http://purl.uniprot.org/core/author | "Nusse R."xsd:string |
| http://purl.uniprot.org/citations/2001840 | http://purl.uniprot.org/core/author | "Nusse R."xsd:string |
| http://purl.uniprot.org/citations/2001840 | http://purl.uniprot.org/core/author | "Roelink H."xsd:string |
| http://purl.uniprot.org/citations/2001840 | http://purl.uniprot.org/core/author | "Roelink H."xsd:string |
| http://purl.uniprot.org/citations/2001840 | http://purl.uniprot.org/core/date | "1991"xsd:gYear |
| http://purl.uniprot.org/citations/2001840 | http://purl.uniprot.org/core/date | "1991"xsd:gYear |
| http://purl.uniprot.org/citations/2001840 | http://purl.uniprot.org/core/name | "Genes Dev."xsd:string |
| http://purl.uniprot.org/citations/2001840 | http://purl.uniprot.org/core/name | "Genes Dev."xsd:string |
| http://purl.uniprot.org/citations/2001840 | http://purl.uniprot.org/core/pages | "381-388"xsd:string |
| http://purl.uniprot.org/citations/2001840 | http://purl.uniprot.org/core/pages | "381-388"xsd:string |
| http://purl.uniprot.org/citations/2001840 | http://purl.uniprot.org/core/title | "Expression of two members of the Wnt family during mouse development -- restricted temporal and spatial patterns in the developing neural tube."xsd:string |
| http://purl.uniprot.org/citations/2001840 | http://purl.uniprot.org/core/title | "Expression of two members of the Wnt family during mouse development -- restricted temporal and spatial patterns in the developing neural tube."xsd:string |
| http://purl.uniprot.org/citations/2001840 | http://purl.uniprot.org/core/volume | "5"xsd:string |
| http://purl.uniprot.org/citations/2001840 | http://purl.uniprot.org/core/volume | "5"xsd:string |
| http://purl.uniprot.org/citations/2001840 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2001840 |
| http://purl.uniprot.org/citations/2001840 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2001840 |
| http://purl.uniprot.org/citations/2001840 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/2001840 |
| http://purl.uniprot.org/citations/2001840 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/2001840 |
| http://purl.uniprot.org/uniprot/P27467 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/2001840 |
| http://purl.uniprot.org/uniprot/#_kb.P27467_up.isolatedFrom_tissue.229 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/2001840 |