| http://purl.uniprot.org/citations/20219467 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20219467 | http://www.w3.org/2000/01/rdf-schema#comment | "MicroRNA-155 (miR-155) has been implicated as a central regulator of the immune system. We have previously reported that miR-155 negatively regulates Helicobacter pylori (H. pylori)-induced inflammation, but the molecular mechanism of miR-155 regulating the inflammation is not fully clear. Here, we identified myeloid differentiation protein 88 (MyD88) as a target gene of miR-155, and found that miR-155 decreased MyD88 expression at the protein but not the mRNA message level, suggesting that the miR-155-mediated inhibition is a post-transcriptional event. Furthermore, the overexpression of miR-155 led to significantly reduced IL-8 production induced by H. pylori infection. Thus, we have demonstrated that miR-155 can negatively regulate inflammation by targeting a key adaptor molecule MyD88 in inflammatory pathways."xsd:string |
| http://purl.uniprot.org/citations/20219467 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2010.02.063"xsd:string |
| http://purl.uniprot.org/citations/20219467 | http://purl.uniprot.org/core/author | "Liu Z."xsd:string |
| http://purl.uniprot.org/citations/20219467 | http://purl.uniprot.org/core/author | "Li N."xsd:string |
| http://purl.uniprot.org/citations/20219467 | http://purl.uniprot.org/core/author | "Tang B."xsd:string |
| http://purl.uniprot.org/citations/20219467 | http://purl.uniprot.org/core/author | "Xiao B."xsd:string |
| http://purl.uniprot.org/citations/20219467 | http://purl.uniprot.org/core/author | "Zou Q.M."xsd:string |
| http://purl.uniprot.org/citations/20219467 | http://purl.uniprot.org/core/author | "Zhuang Y."xsd:string |
| http://purl.uniprot.org/citations/20219467 | http://purl.uniprot.org/core/author | "Mao X.H."xsd:string |
| http://purl.uniprot.org/citations/20219467 | http://purl.uniprot.org/core/author | "Li B.S."xsd:string |
| http://purl.uniprot.org/citations/20219467 | http://purl.uniprot.org/core/author | "Zhu E.D."xsd:string |
| http://purl.uniprot.org/citations/20219467 | http://purl.uniprot.org/core/author | "Xie Q.H."xsd:string |
| http://purl.uniprot.org/citations/20219467 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20219467 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/20219467 | http://purl.uniprot.org/core/pages | "1481-1486"xsd:string |
| http://purl.uniprot.org/citations/20219467 | http://purl.uniprot.org/core/title | "Identification of MyD88 as a novel target of miR-155, involved in negative regulation of Helicobacter pylori-induced inflammation."xsd:string |
| http://purl.uniprot.org/citations/20219467 | http://purl.uniprot.org/core/volume | "584"xsd:string |
| http://purl.uniprot.org/citations/20219467 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20219467 |
| http://purl.uniprot.org/citations/20219467 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/20219467 |
| http://purl.uniprot.org/uniprot/Q99836#attribution-DEEF0219DC7BA131327602BE8C90C5BE | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/20219467 |