| http://purl.uniprot.org/citations/20668183 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20668183 | http://www.w3.org/2000/01/rdf-schema#comment | "Persistent changes in spine shape are coupled to long-lasting synaptic plasticity in hippocampus. The molecules that coordinate such persistent structural and functional plasticity are unknown. Here, we generated mice in which the cell adhesion molecule N-cadherin was conditionally ablated from postnatal, excitatory synapses in hippocampus. We applied to adult mice of either sex a combination of whole-cell recording, two-photon microscopy, and spine morphometric analysis to show that postnatal ablation of N-cadherin has profound effects on the stability of coordinated spine enlargement and long-term potentiation (LTP) at mature CA1 synapses, with no effects on baseline spine density or morphology, baseline properties of synaptic neurotransmission, or long-term depression. Thus, N-cadherin couples persistent spine structural modifications with long-lasting synaptic functional modifications associated selectively with LTP, revealing unexpectedly distinct roles at mature synapses in comparison with earlier, broader functions in synapse and spine development."xsd:string |
| http://purl.uniprot.org/citations/20668183 | http://purl.org/dc/terms/identifier | "doi:10.1523/jneurosci.1223-10.2010"xsd:string |
| http://purl.uniprot.org/citations/20668183 | http://purl.uniprot.org/core/author | "Zhou Q."xsd:string |
| http://purl.uniprot.org/citations/20668183 | http://purl.uniprot.org/core/author | "Wang X.B."xsd:string |
| http://purl.uniprot.org/citations/20668183 | http://purl.uniprot.org/core/author | "Benson D.L."xsd:string |
| http://purl.uniprot.org/citations/20668183 | http://purl.uniprot.org/core/author | "Bozdagi O."xsd:string |
| http://purl.uniprot.org/citations/20668183 | http://purl.uniprot.org/core/author | "Huntley G.W."xsd:string |
| http://purl.uniprot.org/citations/20668183 | http://purl.uniprot.org/core/author | "Radice G.L."xsd:string |
| http://purl.uniprot.org/citations/20668183 | http://purl.uniprot.org/core/author | "Anderson T.R."xsd:string |
| http://purl.uniprot.org/citations/20668183 | http://purl.uniprot.org/core/author | "Bloss E.B."xsd:string |
| http://purl.uniprot.org/citations/20668183 | http://purl.uniprot.org/core/author | "Nikitczuk J.S."xsd:string |
| http://purl.uniprot.org/citations/20668183 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20668183 | http://purl.uniprot.org/core/name | "J Neurosci"xsd:string |
| http://purl.uniprot.org/citations/20668183 | http://purl.uniprot.org/core/pages | "9984-9989"xsd:string |
| http://purl.uniprot.org/citations/20668183 | http://purl.uniprot.org/core/title | "Persistence of coordinated long-term potentiation and dendritic spine enlargement at mature hippocampal CA1 synapses requires N-cadherin."xsd:string |
| http://purl.uniprot.org/citations/20668183 | http://purl.uniprot.org/core/volume | "30"xsd:string |
| http://purl.uniprot.org/citations/20668183 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20668183 |
| http://purl.uniprot.org/citations/20668183 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/20668183 |
| http://purl.uniprot.org/uniprot/P15116#attribution-A2AB2AD7E025B730BC782915F2748EFD | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/20668183 |
| http://purl.uniprot.org/uniprot/#_D3YYT0-mappedCitation-20668183 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20668183 |
| http://purl.uniprot.org/uniprot/#_Q3UIC2-mappedCitation-20668183 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20668183 |
| http://purl.uniprot.org/uniprot/#_Q8BSI9-mappedCitation-20668183 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20668183 |
| http://purl.uniprot.org/uniprot/#_P15116-mappedCitation-20668183 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20668183 |
| http://purl.uniprot.org/uniprot/#_Q80XX1-mappedCitation-20668183 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20668183 |