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http://purl.uniprot.org/citations/20812024http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/20812024http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/20812024http://www.w3.org/2000/01/rdf-schema#comment"The pro-oncogene FBI-1, encoded by Zbtb7a, is a transcriptional repressor that belongs to the POK (POZ/BTB and Krüppel) protein family. In this study, we investigated a potential interaction between androgen receptor (AR) signaling and FBI-1 and demonstrated that overexpression of FBI-1 inhibited ligand-dependent AR activation. A protein-protein interaction was identified between FBI-1 and AR in a ligand-dependent manner. Furthermore, FBI-1, AR and SMRT formed a ternary complex and FBI-1 enhanced the recruitment of NCoR and SMRT to endogenous PSA upstream sequences. Our data also indicated that the FBI-1-mediated inhibition of AR transcriptional activity is partially dependent on HDAC. Interestingly, FBI-1 plays distinct roles in regulating LNCaP (androgen-dependent) and PC-3 cell (androgen-independent) proliferation."xsd:string
http://purl.uniprot.org/citations/20812024http://purl.org/dc/terms/identifier"doi:10.1007/s00018-010-0511-7"xsd:string
http://purl.uniprot.org/citations/20812024http://purl.org/dc/terms/identifier"doi:10.1007/s00018-010-0511-7"xsd:string
http://purl.uniprot.org/citations/20812024http://purl.uniprot.org/core/author"Hu P."xsd:string
http://purl.uniprot.org/citations/20812024http://purl.uniprot.org/core/author"Hu P."xsd:string
http://purl.uniprot.org/citations/20812024http://purl.uniprot.org/core/author"Liu X."xsd:string
http://purl.uniprot.org/citations/20812024http://purl.uniprot.org/core/author"Liu X."xsd:string
http://purl.uniprot.org/citations/20812024http://purl.uniprot.org/core/author"Song H."xsd:string
http://purl.uniprot.org/citations/20812024http://purl.uniprot.org/core/author"Song H."xsd:string
http://purl.uniprot.org/citations/20812024http://purl.uniprot.org/core/author"Zhang C."xsd:string
http://purl.uniprot.org/citations/20812024http://purl.uniprot.org/core/author"Zhang C."xsd:string
http://purl.uniprot.org/citations/20812024http://purl.uniprot.org/core/author"Yang Y."xsd:string
http://purl.uniprot.org/citations/20812024http://purl.uniprot.org/core/author"Yang Y."xsd:string
http://purl.uniprot.org/citations/20812024http://purl.uniprot.org/core/author"Bai X."xsd:string
http://purl.uniprot.org/citations/20812024http://purl.uniprot.org/core/author"Bai X."xsd:string
http://purl.uniprot.org/citations/20812024http://purl.uniprot.org/core/author"Cui J."xsd:string
http://purl.uniprot.org/citations/20812024http://purl.uniprot.org/core/author"Cui J."xsd:string
http://purl.uniprot.org/citations/20812024http://purl.uniprot.org/core/author"Kan W."xsd:string
http://purl.uniprot.org/citations/20812024http://purl.uniprot.org/core/author"Kan W."xsd:string
http://purl.uniprot.org/citations/20812024http://purl.uniprot.org/core/date"2011"xsd:gYear
http://purl.uniprot.org/citations/20812024http://purl.uniprot.org/core/date"2011"xsd:gYear
http://purl.uniprot.org/citations/20812024http://purl.uniprot.org/core/name"Cell. Mol. Life Sci."xsd:string
http://purl.uniprot.org/citations/20812024http://purl.uniprot.org/core/name"Cell. Mol. Life Sci."xsd:string