| http://purl.uniprot.org/citations/21252314 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21252314 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21252314 | http://www.w3.org/2000/01/rdf-schema#comment | "Intracellular pathogens such as Listeria monocytogenes subvert cellular functions through the interaction of bacterial effectors with host components. Here we found that a secreted listerial virulence factor, LntA, could target the chromatin repressor BAHD1 in the host cell nucleus to activate interferon (IFN)-stimulated genes (ISGs). IFN-λ expression was induced in response to infection of epithelial cells with bacteria lacking LntA; however, the BAHD1-chromatin associated complex repressed downstream ISGs. In contrast, in cells infected with lntA-expressing bacteria, LntA prevented BAHD1 recruitment to ISGs and stimulated their expression. Murine listeriosis decreased in BAHD1(+/-) mice or when lntA was constitutively expressed. Thus, the LntA-BAHD1 interplay may modulate IFN-λ-mediated immune response to control bacterial colonization of the host."xsd:string |
| http://purl.uniprot.org/citations/21252314 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1200120"xsd:string |
| http://purl.uniprot.org/citations/21252314 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1200120"xsd:string |
| http://purl.uniprot.org/citations/21252314 | http://purl.uniprot.org/core/author | "Cossart P."xsd:string |
| http://purl.uniprot.org/citations/21252314 | http://purl.uniprot.org/core/author | "Cossart P."xsd:string |
| http://purl.uniprot.org/citations/21252314 | http://purl.uniprot.org/core/author | "Gautreau A."xsd:string |
| http://purl.uniprot.org/citations/21252314 | http://purl.uniprot.org/core/author | "Gautreau A."xsd:string |
| http://purl.uniprot.org/citations/21252314 | http://purl.uniprot.org/core/author | "Lakisic G."xsd:string |
| http://purl.uniprot.org/citations/21252314 | http://purl.uniprot.org/core/author | "Lakisic G."xsd:string |
| http://purl.uniprot.org/citations/21252314 | http://purl.uniprot.org/core/author | "Bierne H."xsd:string |
| http://purl.uniprot.org/citations/21252314 | http://purl.uniprot.org/core/author | "Bierne H."xsd:string |
| http://purl.uniprot.org/citations/21252314 | http://purl.uniprot.org/core/author | "Ait-Si-Ali S."xsd:string |
| http://purl.uniprot.org/citations/21252314 | http://purl.uniprot.org/core/author | "Ait-Si-Ali S."xsd:string |
| http://purl.uniprot.org/citations/21252314 | http://purl.uniprot.org/core/author | "Fritsch L."xsd:string |
| http://purl.uniprot.org/citations/21252314 | http://purl.uniprot.org/core/author | "Fritsch L."xsd:string |
| http://purl.uniprot.org/citations/21252314 | http://purl.uniprot.org/core/author | "Dessen A."xsd:string |
| http://purl.uniprot.org/citations/21252314 | http://purl.uniprot.org/core/author | "Dessen A."xsd:string |
| http://purl.uniprot.org/citations/21252314 | http://purl.uniprot.org/core/author | "Lebreton A."xsd:string |
| http://purl.uniprot.org/citations/21252314 | http://purl.uniprot.org/core/author | "Lebreton A."xsd:string |
| http://purl.uniprot.org/citations/21252314 | http://purl.uniprot.org/core/author | "Regnault B."xsd:string |
| http://purl.uniprot.org/citations/21252314 | http://purl.uniprot.org/core/author | "Regnault B."xsd:string |
| http://purl.uniprot.org/citations/21252314 | http://purl.uniprot.org/core/author | "Cabanes D."xsd:string |
| http://purl.uniprot.org/citations/21252314 | http://purl.uniprot.org/core/author | "Cabanes D."xsd:string |