| http://purl.uniprot.org/citations/21423620 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21423620 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21423620 | http://www.w3.org/2000/01/rdf-schema#comment | "In the endoplasmic reticulum, calreticulin acts as a chaperone and a Ca(2+)-signalling protein. At the cell surface, it mediates numerous important biological effects. The crystal structure of the human calreticulin globular domain was solved at 1.55 Å resolution. Interactions of the flexible N-terminal extension with the edge of the lectin site are consistently observed, revealing a hitherto unidentified peptide-binding site. A calreticulin molecular zipper, observed in all crystal lattices, could further extend this site by creating a binding cavity lined by hydrophobic residues. These data thus provide a first structural insight into the lectin-independent binding properties of calreticulin and suggest new working hypotheses, including that of a multi-molecular mechanism."xsd:string |
| http://purl.uniprot.org/citations/21423620 | http://purl.org/dc/terms/identifier | "doi:10.1371/journal.pone.0017886"xsd:string |
| http://purl.uniprot.org/citations/21423620 | http://purl.org/dc/terms/identifier | "doi:10.1371/journal.pone.0017886"xsd:string |
| http://purl.uniprot.org/citations/21423620 | http://purl.uniprot.org/core/author | "Chouquet A."xsd:string |
| http://purl.uniprot.org/citations/21423620 | http://purl.uniprot.org/core/author | "Chouquet A."xsd:string |
| http://purl.uniprot.org/citations/21423620 | http://purl.uniprot.org/core/author | "Gaboriaud C."xsd:string |
| http://purl.uniprot.org/citations/21423620 | http://purl.uniprot.org/core/author | "Gaboriaud C."xsd:string |
| http://purl.uniprot.org/citations/21423620 | http://purl.uniprot.org/core/author | "Arlaud G.J."xsd:string |
| http://purl.uniprot.org/citations/21423620 | http://purl.uniprot.org/core/author | "Arlaud G.J."xsd:string |
| http://purl.uniprot.org/citations/21423620 | http://purl.uniprot.org/core/author | "Ling W.L."xsd:string |
| http://purl.uniprot.org/citations/21423620 | http://purl.uniprot.org/core/author | "Ling W.L."xsd:string |
| http://purl.uniprot.org/citations/21423620 | http://purl.uniprot.org/core/author | "Houen G."xsd:string |
| http://purl.uniprot.org/citations/21423620 | http://purl.uniprot.org/core/author | "Houen G."xsd:string |
| http://purl.uniprot.org/citations/21423620 | http://purl.uniprot.org/core/author | "Frachet P."xsd:string |
| http://purl.uniprot.org/citations/21423620 | http://purl.uniprot.org/core/author | "Frachet P."xsd:string |
| http://purl.uniprot.org/citations/21423620 | http://purl.uniprot.org/core/author | "Paidassi H."xsd:string |
| http://purl.uniprot.org/citations/21423620 | http://purl.uniprot.org/core/author | "Paidassi H."xsd:string |
| http://purl.uniprot.org/citations/21423620 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21423620 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21423620 | http://purl.uniprot.org/core/name | "PLoS ONE"xsd:string |
| http://purl.uniprot.org/citations/21423620 | http://purl.uniprot.org/core/name | "PLoS ONE"xsd:string |
| http://purl.uniprot.org/citations/21423620 | http://purl.uniprot.org/core/pages | "E17886"xsd:string |
| http://purl.uniprot.org/citations/21423620 | http://purl.uniprot.org/core/pages | "E17886"xsd:string |