| http://purl.uniprot.org/citations/21429299 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21429299 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21429299 | http://www.w3.org/2000/01/rdf-schema#comment | "Ephrin signaling is involved in various morphogenetic events, such as axon guidance, hindbrain segmentation, and angiogenesis. We conducted a yeast two-hybrid screen using the intracellular domain (ICD) of EphrinB1 to gain biochemical insightinto the function of the EphrinB1 ICD. We identified the transcriptional co-repressor xTLE1/Groucho as an EphrinB1 interacting protein. Whole-mount in situ hybridization of Xenopus embryos confirmed the co-localization of EphrinB1 and a Xenopus counterpart to TLE1, xTLE4, during various stages of development. The EphrinB1/xTLE4 interaction was confirmed by co-immunoprecipitation experiments. Further characterization of the interaction revealed that the carboxy-terminal PDZ binding motif of EphrinB1 and the SP domain of xTLE4 are required for binding. Additionally, phosphorylation of EphrinB1 by a constitutively activated fibroblast growth factor receptor resulted in loss of the interaction, suggesting that the interaction is modulated by tyrosine phosphorylation of the EphrinB1 ICD."xsd:string |
| http://purl.uniprot.org/citations/21429299 | http://purl.org/dc/terms/identifier | "doi:10.5483/bmbrep.2011.44.3.199"xsd:string |
| http://purl.uniprot.org/citations/21429299 | http://purl.org/dc/terms/identifier | "doi:10.5483/bmbrep.2011.44.3.199"xsd:string |
| http://purl.uniprot.org/citations/21429299 | http://purl.uniprot.org/core/author | "Lee H.S."xsd:string |
| http://purl.uniprot.org/citations/21429299 | http://purl.uniprot.org/core/author | "Lee H.S."xsd:string |
| http://purl.uniprot.org/citations/21429299 | http://purl.uniprot.org/core/author | "Kamata T."xsd:string |
| http://purl.uniprot.org/citations/21429299 | http://purl.uniprot.org/core/author | "Kamata T."xsd:string |
| http://purl.uniprot.org/citations/21429299 | http://purl.uniprot.org/core/author | "Park M.J."xsd:string |
| http://purl.uniprot.org/citations/21429299 | http://purl.uniprot.org/core/author | "Park M.J."xsd:string |
| http://purl.uniprot.org/citations/21429299 | http://purl.uniprot.org/core/author | "Nishanian T.G."xsd:string |
| http://purl.uniprot.org/citations/21429299 | http://purl.uniprot.org/core/author | "Nishanian T.G."xsd:string |
| http://purl.uniprot.org/citations/21429299 | http://purl.uniprot.org/core/author | "Bong Y.S."xsd:string |
| http://purl.uniprot.org/citations/21429299 | http://purl.uniprot.org/core/author | "Bong Y.S."xsd:string |
| http://purl.uniprot.org/citations/21429299 | http://purl.uniprot.org/core/author | "Mood K."xsd:string |
| http://purl.uniprot.org/citations/21429299 | http://purl.uniprot.org/core/author | "Mood K."xsd:string |
| http://purl.uniprot.org/citations/21429299 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21429299 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21429299 | http://purl.uniprot.org/core/name | "BMB Rep."xsd:string |
| http://purl.uniprot.org/citations/21429299 | http://purl.uniprot.org/core/name | "BMB Rep."xsd:string |
| http://purl.uniprot.org/citations/21429299 | http://purl.uniprot.org/core/pages | "199-204"xsd:string |
| http://purl.uniprot.org/citations/21429299 | http://purl.uniprot.org/core/pages | "199-204"xsd:string |
| http://purl.uniprot.org/citations/21429299 | http://purl.uniprot.org/core/title | "EphrinB1 interacts with the transcriptional co-repressor Groucho/xTLE4."xsd:string |
| http://purl.uniprot.org/citations/21429299 | http://purl.uniprot.org/core/title | "EphrinB1 interacts with the transcriptional co-repressor Groucho/xTLE4."xsd:string |