DESCRIBE <http://purl.uniprot.org/citations/21805676>

Subject	Predicate	Object
http://purl.uniprot.org/citations/21805676	http://www.w3.org/1999/02/22-rdf-syntax-ns#type	http://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/21805676	http://www.w3.org/2000/01/rdf-schema#comment	" Purpose Respiratory syncytial virus (RSV) is the most common cause of severe respiratory tract infection in infants. The aim was to identify host defence components in nasopharyngeal aspirate (NPA) from infants with RSV infection and to study the expression of the novel 25 kDa innate immunity protein SPLUNC1. Experimental design NPAs from infants were analyzed with 2-DE and MS in a pilot study. The levels of SPLUNC1 were analyzed with immunoblotting in 47 NPAs, admitted for RSV diagnosis. Results Totally, 35 proteins were identified in NPA, including several innate immunity proteins such as group X phospholipase A(2) , different S100 proteins and SPLUNC1. In addition, a new truncated 15 kDa form of SPLUNC1 was identified that was detected in about 50% of the aspirates admitted for RSV diagnosis. RSV-positive boys had significantly less 25 kDa SPLUNC1 than RSV-negative boys while there were no significant differences among girls. Conclusions and clinical relevance Several important innate immunity proteins were identified in NPA. Notably, a new truncated form of the newly suggested anti-bacterial protein SPLUNC1 was found. It is possible that a decrease in SPLUNC1 in the upper airways may increase the risk for severe pneumonia in boys."xsd:string
http://purl.uniprot.org/citations/21805676	http://purl.org/dc/terms/identifier	"doi:10.1002/prca.201100016"xsd:string
http://purl.uniprot.org/citations/21805676	http://purl.uniprot.org/core/author	"Lindahl M."xsd:string
http://purl.uniprot.org/citations/21805676	http://purl.uniprot.org/core/author	"Ghafouri B."xsd:string
http://purl.uniprot.org/citations/21805676	http://purl.uniprot.org/core/author	"Tagesson C."xsd:string
http://purl.uniprot.org/citations/21805676	http://purl.uniprot.org/core/author	"Akerlind B."xsd:string
http://purl.uniprot.org/citations/21805676	http://purl.uniprot.org/core/author	"Fornander L."xsd:string
http://purl.uniprot.org/citations/21805676	http://purl.uniprot.org/core/author	"Kihlstrom E."xsd:string
http://purl.uniprot.org/citations/21805676	http://purl.uniprot.org/core/author	"Schon T."xsd:string
http://purl.uniprot.org/citations/21805676	http://purl.uniprot.org/core/date	"2011"xsd:gYear
http://purl.uniprot.org/citations/21805676	http://purl.uniprot.org/core/name	"Proteomics Clin Appl"xsd:string
http://purl.uniprot.org/citations/21805676	http://purl.uniprot.org/core/pages	"513-522"xsd:string
http://purl.uniprot.org/citations/21805676	http://purl.uniprot.org/core/title	"Innate immunity proteins and a new truncated form of SPLUNC1 in nasopharyngeal aspirates from infants with respiratory syncytial virus infection."xsd:string
http://purl.uniprot.org/citations/21805676	http://purl.uniprot.org/core/volume	"5"xsd:string
http://purl.uniprot.org/citations/21805676	http://www.w3.org/2004/02/skos/core#exactMatch	http://purl.uniprot.org/pubmed/21805676
http://purl.uniprot.org/citations/21805676	http://xmlns.com/foaf/0.1/primaryTopicOf	https://pubmed.ncbi.nlm.nih.gov/21805676
http://purl.uniprot.org/uniprot/P02768#attribution-CB9106FBA42CDF935A5B8083F7F90D34	http://purl.uniprot.org/core/source	http://purl.uniprot.org/citations/21805676
http://purl.uniprot.org/uniprot/Q9NP55#attribution-3E10D52096EAB8E269EF157B7CCDFD15	http://purl.uniprot.org/core/source	http://purl.uniprot.org/citations/21805676
http://purl.uniprot.org/uniprot/Q9NP55#attribution-CB9106FBA42CDF935A5B8083F7F90D34	http://purl.uniprot.org/core/source	http://purl.uniprot.org/citations/21805676
http://purl.uniprot.org/uniprot/Q5W188#attribution-CB9106FBA42CDF935A5B8083F7F90D34	http://purl.uniprot.org/core/source	http://purl.uniprot.org/citations/21805676
http://purl.uniprot.org/uniprot/P69905#attribution-CB9106FBA42CDF935A5B8083F7F90D34	http://purl.uniprot.org/core/source	http://purl.uniprot.org/citations/21805676
http://purl.uniprot.org/uniprot/P68871#attribution-CB9106FBA42CDF935A5B8083F7F90D34	http://purl.uniprot.org/core/source	http://purl.uniprot.org/citations/21805676
http://purl.uniprot.org/uniprot/P00738#attribution-CB9106FBA42CDF935A5B8083F7F90D34	http://purl.uniprot.org/core/source	http://purl.uniprot.org/citations/21805676
http://purl.uniprot.org/uniprot/P61626#attribution-CB9106FBA42CDF935A5B8083F7F90D34	http://purl.uniprot.org/core/source	http://purl.uniprot.org/citations/21805676