| http://purl.uniprot.org/citations/21836637 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21836637 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/21836637 | http://www.w3.org/2000/01/rdf-schema#comment | "Covalent attachment of small ubiquitin-like modifier (SUMO) to proteins regulates many processes in the eukaryotic cell. This reaction is similar to ubiquitination and usually requires an E3 ligase for substrate modification. However, only a few SUMO ligases have been described so far, which frequently facilitate sumoylation by bringing together the SUMO-conjugating enzyme Ubc9 and the target protein. Ubc9 is an interaction partner of the transcription factor Krox20, a key regulator of hindbrain development. Here, we show that Krox20 functions as a SUMO ligase for its coregulators--the Nab proteins--and that Nab sumoylation negatively modulates Krox20 transcriptional activity in vivo."xsd:string |
| http://purl.uniprot.org/citations/21836637 | http://purl.org/dc/terms/identifier | "doi:10.1038/embor.2011.152"xsd:string |
| http://purl.uniprot.org/citations/21836637 | http://purl.org/dc/terms/identifier | "doi:10.1038/embor.2011.152"xsd:string |
| http://purl.uniprot.org/citations/21836637 | http://purl.uniprot.org/core/author | "Charnay P."xsd:string |
| http://purl.uniprot.org/citations/21836637 | http://purl.uniprot.org/core/author | "Charnay P."xsd:string |
| http://purl.uniprot.org/citations/21836637 | http://purl.uniprot.org/core/author | "Garcia-Dominguez M."xsd:string |
| http://purl.uniprot.org/citations/21836637 | http://purl.uniprot.org/core/author | "Garcia-Dominguez M."xsd:string |
| http://purl.uniprot.org/citations/21836637 | http://purl.uniprot.org/core/author | "Gallardo-Chamizo F."xsd:string |
| http://purl.uniprot.org/citations/21836637 | http://purl.uniprot.org/core/author | "Gallardo-Chamizo F."xsd:string |
| http://purl.uniprot.org/citations/21836637 | http://purl.uniprot.org/core/author | "Garcia-Gutierrez P."xsd:string |
| http://purl.uniprot.org/citations/21836637 | http://purl.uniprot.org/core/author | "Garcia-Gutierrez P."xsd:string |
| http://purl.uniprot.org/citations/21836637 | http://purl.uniprot.org/core/author | "Juarez-Vicente F."xsd:string |
| http://purl.uniprot.org/citations/21836637 | http://purl.uniprot.org/core/author | "Juarez-Vicente F."xsd:string |
| http://purl.uniprot.org/citations/21836637 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21836637 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
| http://purl.uniprot.org/citations/21836637 | http://purl.uniprot.org/core/name | "EMBO Rep."xsd:string |
| http://purl.uniprot.org/citations/21836637 | http://purl.uniprot.org/core/name | "EMBO Rep."xsd:string |
| http://purl.uniprot.org/citations/21836637 | http://purl.uniprot.org/core/pages | "1018-1023"xsd:string |
| http://purl.uniprot.org/citations/21836637 | http://purl.uniprot.org/core/pages | "1018-1023"xsd:string |
| http://purl.uniprot.org/citations/21836637 | http://purl.uniprot.org/core/title | "The transcription factor Krox20 is an E3 ligase that sumoylates its Nab coregulators."xsd:string |
| http://purl.uniprot.org/citations/21836637 | http://purl.uniprot.org/core/title | "The transcription factor Krox20 is an E3 ligase that sumoylates its Nab coregulators."xsd:string |
| http://purl.uniprot.org/citations/21836637 | http://purl.uniprot.org/core/volume | "12"xsd:string |
| http://purl.uniprot.org/citations/21836637 | http://purl.uniprot.org/core/volume | "12"xsd:string |