http://purl.uniprot.org/citations/22039842 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/22039842 | http://www.w3.org/2000/01/rdf-schema#comment | "BackgroundWe investigated the association between apolipoprotein E polymorphism and ischemic heart disease with or without type 2 diabetes in Kuwait and examined the impact of apolipoprotein E polymorphism in diabetic patients.MethodsThe present study was conducted from January 2005 to June 2006 in the Diabetic Clinic of Al-Amiri and Al-Sabah Hospitals in Kuwait City. Apolipoprotein E polymorphism was assessed in 250 subjects of which 83 were ischemic heart disease patients (41 diabetic and 42 non-diabetic) and 105 were diabetic patients without ischemic heart disease. Results were compared with 62 healthy controls. Apolipoprotein E polymorphisms were detected by polymerase chain reaction-restriction fragment length polymorphism.ResultsApolipoprotein E3 allele was the most commonly occurring form. The frequency of apolipoprotein E4 was higher in ischemic heart disease patients with type 2 diabetes (39%) and the non-diabetic (31%) group, but lower in the diabetic (20%) and control groups (16%).ConclusionApolipoprotein E4 allele may be related to the development of ischemic heart disease in patients with or without type 2 diabetes in Kuwait. However, future studies with larger population sizes are needed to establish such relationship."xsd:string |
http://purl.uniprot.org/citations/22039842 | http://purl.uniprot.org/core/author | "Al-Majed H.T."xsd:string |
http://purl.uniprot.org/citations/22039842 | http://purl.uniprot.org/core/author | "Abdullah S.A."xsd:string |
http://purl.uniprot.org/citations/22039842 | http://purl.uniprot.org/core/author | "Al-Attar A.A."xsd:string |
http://purl.uniprot.org/citations/22039842 | http://purl.uniprot.org/core/author | "Al-Sherifi A.K."xsd:string |
http://purl.uniprot.org/citations/22039842 | http://purl.uniprot.org/core/author | "Qasem A.A."xsd:string |
http://purl.uniprot.org/citations/22039842 | http://purl.uniprot.org/core/author | "Qasem J.A."xsd:string |
http://purl.uniprot.org/citations/22039842 | http://purl.uniprot.org/core/date | "2011"xsd:gYear |
http://purl.uniprot.org/citations/22039842 | http://purl.uniprot.org/core/name | "Arch Iran Med"xsd:string |
http://purl.uniprot.org/citations/22039842 | http://purl.uniprot.org/core/pages | "385-388"xsd:string |
http://purl.uniprot.org/citations/22039842 | http://purl.uniprot.org/core/title | "Association between apolipoprotein E-polymorphism and Ischemic heart disease patients with or without type 2 diabetes mellitus: a preliminary study in Kuwait."xsd:string |
http://purl.uniprot.org/citations/22039842 | http://purl.uniprot.org/core/volume | "14"xsd:string |
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