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http://purl.uniprot.org/citations/2251254http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2251254http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2251254http://www.w3.org/2000/01/rdf-schema#comment"Two types of cDNAs for human macrophage scavenger receptors were cloned from a cDNA library derived from the phorbol ester-treated human monocytic cell line THP-1. The type I and type II human scavenger receptors encoded by these cDNAs are homologous (73% and 71% amino acid identity) to their previously characterized bovine counterparts and consist of six domains: cytoplasmic (I), membrane-spanning (II), spacer (III), alpha-helical coiled-coil (IV), collagen-like (V), and a type-specific C-terminal (VI). The receptor gene is located on human chromosome 8. The human receptors expressed in CHO-K1 cells mediated endocytosis of modified low density lipoproteins. Two mRNAs, 4.0 and 3.2 kilobases, have been detected in human liver, placenta, and brain. Immunohistochemical studies using an anti-peptide antibody which recognizes human scavenger receptors indicated the presence of the scavenger receptors in the macrophages of lipid-rich atherosclerotic lesions, suggesting the involvement of scavenger receptors in atherogenesis."xsd:string
http://purl.uniprot.org/citations/2251254http://purl.org/dc/terms/identifier"doi:10.1073/pnas.87.23.9133"xsd:string
http://purl.uniprot.org/citations/2251254http://purl.org/dc/terms/identifier"doi:10.1073/pnas.87.23.9133"xsd:string
http://purl.uniprot.org/citations/2251254http://purl.uniprot.org/core/author"Kodama T."xsd:string
http://purl.uniprot.org/citations/2251254http://purl.uniprot.org/core/author"Kodama T."xsd:string
http://purl.uniprot.org/citations/2251254http://purl.uniprot.org/core/author"Wydro R."xsd:string
http://purl.uniprot.org/citations/2251254http://purl.uniprot.org/core/author"Wydro R."xsd:string
http://purl.uniprot.org/citations/2251254http://purl.uniprot.org/core/author"Kanamori H."xsd:string
http://purl.uniprot.org/citations/2251254http://purl.uniprot.org/core/author"Kanamori H."xsd:string
http://purl.uniprot.org/citations/2251254http://purl.uniprot.org/core/author"Suzuki H."xsd:string
http://purl.uniprot.org/citations/2251254http://purl.uniprot.org/core/author"Suzuki H."xsd:string
http://purl.uniprot.org/citations/2251254http://purl.uniprot.org/core/author"Takahashi K."xsd:string
http://purl.uniprot.org/citations/2251254http://purl.uniprot.org/core/author"Takahashi K."xsd:string
http://purl.uniprot.org/citations/2251254http://purl.uniprot.org/core/author"Naito M."xsd:string
http://purl.uniprot.org/citations/2251254http://purl.uniprot.org/core/author"Naito M."xsd:string
http://purl.uniprot.org/citations/2251254http://purl.uniprot.org/core/author"Matsumoto A."xsd:string
http://purl.uniprot.org/citations/2251254http://purl.uniprot.org/core/author"Matsumoto A."xsd:string
http://purl.uniprot.org/citations/2251254http://purl.uniprot.org/core/author"Takaku F."xsd:string
http://purl.uniprot.org/citations/2251254http://purl.uniprot.org/core/author"Takaku F."xsd:string
http://purl.uniprot.org/citations/2251254http://purl.uniprot.org/core/author"Ikemoto S."xsd:string
http://purl.uniprot.org/citations/2251254http://purl.uniprot.org/core/author"Ikemoto S."xsd:string
http://purl.uniprot.org/citations/2251254http://purl.uniprot.org/core/author"Aburatani H."xsd:string
http://purl.uniprot.org/citations/2251254http://purl.uniprot.org/core/author"Aburatani H."xsd:string