http://purl.uniprot.org/citations/23106386 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/23106386 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/23106386 | http://www.w3.org/2000/01/rdf-schema#comment | "Casein kinase 1 epsilon (CK1ε) and its closest homologue CK1δ are key regulators of diverse cellular processes. We report two crystal structures of PF4800567, a potent and selective inhibitor of CK1ε, bound to the kinase domains of human CK1ε and CK1δ as well as one apo CK1ε crystal structure. These structures provide a molecular basis for the strong and specific inhibitor interactions with CK1ε and suggest clues for further development of CK1δ inhibitors."xsd:string |
http://purl.uniprot.org/citations/23106386 | http://purl.org/dc/terms/identifier | "doi:10.1021/jm301336n"xsd:string |
http://purl.uniprot.org/citations/23106386 | http://purl.org/dc/terms/identifier | "doi:10.1021/jm301336n"xsd:string |
http://purl.uniprot.org/citations/23106386 | http://purl.uniprot.org/core/author | "Huang X."xsd:string |
http://purl.uniprot.org/citations/23106386 | http://purl.uniprot.org/core/author | "Huang X."xsd:string |
http://purl.uniprot.org/citations/23106386 | http://purl.uniprot.org/core/author | "Zhao H."xsd:string |
http://purl.uniprot.org/citations/23106386 | http://purl.uniprot.org/core/author | "Zhao H."xsd:string |
http://purl.uniprot.org/citations/23106386 | http://purl.uniprot.org/core/author | "Long A.M."xsd:string |
http://purl.uniprot.org/citations/23106386 | http://purl.uniprot.org/core/author | "Long A.M."xsd:string |
http://purl.uniprot.org/citations/23106386 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
http://purl.uniprot.org/citations/23106386 | http://purl.uniprot.org/core/date | "2012"xsd:gYear |
http://purl.uniprot.org/citations/23106386 | http://purl.uniprot.org/core/name | "J. Med. Chem."xsd:string |
http://purl.uniprot.org/citations/23106386 | http://purl.uniprot.org/core/name | "J. Med. Chem."xsd:string |
http://purl.uniprot.org/citations/23106386 | http://purl.uniprot.org/core/pages | "10307-10311"xsd:string |
http://purl.uniprot.org/citations/23106386 | http://purl.uniprot.org/core/pages | "10307-10311"xsd:string |
http://purl.uniprot.org/citations/23106386 | http://purl.uniprot.org/core/title | "Structural basis for the potent and selective inhibition of casein kinase 1 epsilon."xsd:string |
http://purl.uniprot.org/citations/23106386 | http://purl.uniprot.org/core/title | "Structural basis for the potent and selective inhibition of casein kinase 1 epsilon."xsd:string |
http://purl.uniprot.org/citations/23106386 | http://purl.uniprot.org/core/volume | "55"xsd:string |
http://purl.uniprot.org/citations/23106386 | http://purl.uniprot.org/core/volume | "55"xsd:string |
http://purl.uniprot.org/citations/23106386 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23106386 |
http://purl.uniprot.org/citations/23106386 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23106386 |
http://purl.uniprot.org/citations/23106386 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23106386 |
http://purl.uniprot.org/citations/23106386 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23106386 |