http://purl.uniprot.org/citations/23376057 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/23376057 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/23376057 | http://www.w3.org/2000/01/rdf-schema#comment | "The topology of the plasma membrane Na(+)/Ca(2+) exchanger of cardiac muscle, NCX1, is uncertain. Biochemical analyses have indicated the presence of 9 transmembrane segments (TMSs) whereas the recent crystal structure of a prokaryotic homologue has 10 TMSs. The discrepancy is towards the C-terminus of the proteins where the prokaryotic homologue has an additional TMS8. To resolve this apparent disagreement, we re-assessed the topology of the C-terminal TMSs of NCX1. We examined the ability of internal or external cysteine residues in the N-terminal portion of NCX1 to crosslink with cysteine residues, of uncertain orientation, in the C-terminal portion of the protein. The results strongly support a model of NCX1 with 10 TMSs as found in the prokaryotic homologue."xsd:string |
http://purl.uniprot.org/citations/23376057 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.yjmcc.2013.01.010"xsd:string |
http://purl.uniprot.org/citations/23376057 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.yjmcc.2013.01.010"xsd:string |
http://purl.uniprot.org/citations/23376057 | http://purl.uniprot.org/core/author | "Ren X."xsd:string |
http://purl.uniprot.org/citations/23376057 | http://purl.uniprot.org/core/author | "Ren X."xsd:string |
http://purl.uniprot.org/citations/23376057 | http://purl.uniprot.org/core/author | "Philipson K.D."xsd:string |
http://purl.uniprot.org/citations/23376057 | http://purl.uniprot.org/core/author | "Philipson K.D."xsd:string |
http://purl.uniprot.org/citations/23376057 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
http://purl.uniprot.org/citations/23376057 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
http://purl.uniprot.org/citations/23376057 | http://purl.uniprot.org/core/name | "J. Mol. Cell. Cardiol."xsd:string |
http://purl.uniprot.org/citations/23376057 | http://purl.uniprot.org/core/name | "J. Mol. Cell. Cardiol."xsd:string |
http://purl.uniprot.org/citations/23376057 | http://purl.uniprot.org/core/pages | "68-71"xsd:string |
http://purl.uniprot.org/citations/23376057 | http://purl.uniprot.org/core/pages | "68-71"xsd:string |
http://purl.uniprot.org/citations/23376057 | http://purl.uniprot.org/core/title | "The topology of the cardiac Na(+)/Ca(2)(+) exchanger, NCX1."xsd:string |
http://purl.uniprot.org/citations/23376057 | http://purl.uniprot.org/core/title | "The topology of the cardiac Na(+)/Ca(2)(+) exchanger, NCX1."xsd:string |
http://purl.uniprot.org/citations/23376057 | http://purl.uniprot.org/core/volume | "57"xsd:string |
http://purl.uniprot.org/citations/23376057 | http://purl.uniprot.org/core/volume | "57"xsd:string |
http://purl.uniprot.org/citations/23376057 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23376057 |
http://purl.uniprot.org/citations/23376057 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/23376057 |
http://purl.uniprot.org/citations/23376057 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23376057 |
http://purl.uniprot.org/citations/23376057 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/23376057 |
http://purl.uniprot.org/uniprot/P32418 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/23376057 |
http://purl.uniprot.org/uniprot/P32418#attribution-485549F241E43F2232B4A2A7610C2643 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/23376057 |