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http://purl.uniprot.org/citations/23912081http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/23912081http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/23912081http://www.w3.org/2000/01/rdf-schema#comment"Hepatitis B x antigen up-regulates the liver expression of URG7 that contributes to sustain chronic virus infection and to increase the risk for hepatocellular carcinoma by its anti-apoptotic activity. We have investigated the subcellular localization of URG7 expressed in HepG2 cells and determined its membrane topology by glycosylation mapping in vitro. The results demonstrate that URG7 is N-glycosylated and located to the endoplasmic reticulum membrane with an Nlumen-Ccytosol orientation. The results imply that the anti-apoptotic effect of URG7 could arise from the C-terminal cytosolic tail binding a pro-apoptotic signaling factor and retaining it to the endoplasmic reticulum membrane."xsd:string
http://purl.uniprot.org/citations/23912081http://purl.org/dc/terms/identifier"doi:10.1016/j.febslet.2013.07.042"xsd:string
http://purl.uniprot.org/citations/23912081http://purl.org/dc/terms/identifier"doi:10.1016/j.febslet.2013.07.042"xsd:string
http://purl.uniprot.org/citations/23912081http://purl.uniprot.org/core/author"Lara P."xsd:string
http://purl.uniprot.org/citations/23912081http://purl.uniprot.org/core/author"Lara P."xsd:string
http://purl.uniprot.org/citations/23912081http://purl.uniprot.org/core/author"Monne M."xsd:string
http://purl.uniprot.org/citations/23912081http://purl.uniprot.org/core/author"Monne M."xsd:string
http://purl.uniprot.org/citations/23912081http://purl.uniprot.org/core/author"Lasorsa F.M."xsd:string
http://purl.uniprot.org/citations/23912081http://purl.uniprot.org/core/author"Lasorsa F.M."xsd:string
http://purl.uniprot.org/citations/23912081http://purl.uniprot.org/core/author"Nilsson I."xsd:string
http://purl.uniprot.org/citations/23912081http://purl.uniprot.org/core/author"Nilsson I."xsd:string
http://purl.uniprot.org/citations/23912081http://purl.uniprot.org/core/author"Bisaccia F."xsd:string
http://purl.uniprot.org/citations/23912081http://purl.uniprot.org/core/author"Bisaccia F."xsd:string
http://purl.uniprot.org/citations/23912081http://purl.uniprot.org/core/author"Armentano M.F."xsd:string
http://purl.uniprot.org/citations/23912081http://purl.uniprot.org/core/author"Armentano M.F."xsd:string
http://purl.uniprot.org/citations/23912081http://purl.uniprot.org/core/author"Carmosino M."xsd:string
http://purl.uniprot.org/citations/23912081http://purl.uniprot.org/core/author"Carmosino M."xsd:string
http://purl.uniprot.org/citations/23912081http://purl.uniprot.org/core/author"Miglionico R."xsd:string
http://purl.uniprot.org/citations/23912081http://purl.uniprot.org/core/author"Miglionico R."xsd:string
http://purl.uniprot.org/citations/23912081http://purl.uniprot.org/core/author"Monnich M."xsd:string
http://purl.uniprot.org/citations/23912081http://purl.uniprot.org/core/author"Monnich M."xsd:string
http://purl.uniprot.org/citations/23912081http://purl.uniprot.org/core/author"Ostuni A."xsd:string
http://purl.uniprot.org/citations/23912081http://purl.uniprot.org/core/author"Ostuni A."xsd:string