| http://purl.uniprot.org/citations/23913046 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/23913046 | http://www.w3.org/2000/01/rdf-schema#comment | "Defense against attaching-and-effacing bacteria requires the sequential generation of interleukin 23 (IL-23) and IL-22 to induce protective mucosal responses. Although CD4(+) and NKp46(+) innate lymphoid cells (ILCs) are the critical source of IL-22 during infection, the precise source of IL-23 is unclear. We used genetic techniques to deplete mice of specific subsets of classical dendritic cells (cDCs) and analyzed immunity to the attaching-and-effacing pathogen Citrobacter rodentium. We found that the signaling receptor Notch2 controlled the terminal stage of cDC differentiation. Notch2-dependent intestinal CD11b(+) cDCs were an obligate source of IL-23 required for survival after infection with C. rodentium, but CD103(+) cDCs dependent on the transcription factor Batf3 were not. Our results demonstrate a nonredundant function for CD11b(+) cDCs in the response to pathogens in vivo."xsd:string |
| http://purl.uniprot.org/citations/23913046 | http://purl.org/dc/terms/identifier | "doi:10.1038/ni.2679"xsd:string |
| http://purl.uniprot.org/citations/23913046 | http://purl.uniprot.org/core/author | "Lee J.S."xsd:string |
| http://purl.uniprot.org/citations/23913046 | http://purl.uniprot.org/core/author | "Ng D."xsd:string |
| http://purl.uniprot.org/citations/23913046 | http://purl.uniprot.org/core/author | "Song C."xsd:string |
| http://purl.uniprot.org/citations/23913046 | http://purl.uniprot.org/core/author | "Wu X."xsd:string |
| http://purl.uniprot.org/citations/23913046 | http://purl.uniprot.org/core/author | "Kc W."xsd:string |
| http://purl.uniprot.org/citations/23913046 | http://purl.uniprot.org/core/author | "Stappenbeck T.S."xsd:string |
| http://purl.uniprot.org/citations/23913046 | http://purl.uniprot.org/core/author | "Thomas S.R."xsd:string |
| http://purl.uniprot.org/citations/23913046 | http://purl.uniprot.org/core/author | "Colonna M."xsd:string |
| http://purl.uniprot.org/citations/23913046 | http://purl.uniprot.org/core/author | "Kopan R."xsd:string |
| http://purl.uniprot.org/citations/23913046 | http://purl.uniprot.org/core/author | "Murphy K.M."xsd:string |
| http://purl.uniprot.org/citations/23913046 | http://purl.uniprot.org/core/author | "Satpathy A.T."xsd:string |
| http://purl.uniprot.org/citations/23913046 | http://purl.uniprot.org/core/author | "Lee W.L."xsd:string |
| http://purl.uniprot.org/citations/23913046 | http://purl.uniprot.org/core/author | "Murphy T.L."xsd:string |
| http://purl.uniprot.org/citations/23913046 | http://purl.uniprot.org/core/author | "Ouyang W."xsd:string |
| http://purl.uniprot.org/citations/23913046 | http://purl.uniprot.org/core/author | "McDonald K.G."xsd:string |
| http://purl.uniprot.org/citations/23913046 | http://purl.uniprot.org/core/author | "Newberry R.D."xsd:string |
| http://purl.uniprot.org/citations/23913046 | http://purl.uniprot.org/core/author | "Nussenzweig M.C."xsd:string |
| http://purl.uniprot.org/citations/23913046 | http://purl.uniprot.org/core/author | "Guidos C.J."xsd:string |
| http://purl.uniprot.org/citations/23913046 | http://purl.uniprot.org/core/author | "Meredith M.M."xsd:string |
| http://purl.uniprot.org/citations/23913046 | http://purl.uniprot.org/core/author | "Manieri N.A."xsd:string |
| http://purl.uniprot.org/citations/23913046 | http://purl.uniprot.org/core/author | "Briseno C.G."xsd:string |
| http://purl.uniprot.org/citations/23913046 | http://purl.uniprot.org/core/author | "Gommerman J.L."xsd:string |