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http://purl.uniprot.org/citations/24498420http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/24498420http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/24498420http://www.w3.org/2000/01/rdf-schema#comment"ERα functions are tightly controlled by numerous post-translational modifications including arginine methylation, which is required to mediate the extranuclear functions of the receptor. We report that upon oestrogenic stimulation, JMJD6, the only arginine demethylase described so far, interacts with and regulates methylated ERα (metERα) function. Moreover, by combining the silencing of JMJD6 with demethylation assays, we show that metERα is a new substrate for JMJD6. We propose that the demethylase activity of JMJD6 is a decisive regulator of the rapid physiological responses to oestrogen."xsd:string
http://purl.uniprot.org/citations/24498420http://purl.org/dc/terms/identifier"doi:10.1371/journal.pone.0087982"xsd:string
http://purl.uniprot.org/citations/24498420http://purl.org/dc/terms/identifier"doi:10.1371/journal.pone.0087982"xsd:string
http://purl.uniprot.org/citations/24498420http://purl.uniprot.org/core/author"Corbo L."xsd:string
http://purl.uniprot.org/citations/24498420http://purl.uniprot.org/core/author"Corbo L."xsd:string
http://purl.uniprot.org/citations/24498420http://purl.uniprot.org/core/author"Le Romancer M."xsd:string
http://purl.uniprot.org/citations/24498420http://purl.uniprot.org/core/author"Le Romancer M."xsd:string
http://purl.uniprot.org/citations/24498420http://purl.uniprot.org/core/author"Hussein N."xsd:string
http://purl.uniprot.org/citations/24498420http://purl.uniprot.org/core/author"Hussein N."xsd:string
http://purl.uniprot.org/citations/24498420http://purl.uniprot.org/core/author"Poulard C."xsd:string
http://purl.uniprot.org/citations/24498420http://purl.uniprot.org/core/author"Poulard C."xsd:string
http://purl.uniprot.org/citations/24498420http://purl.uniprot.org/core/author"Rambaud J."xsd:string
http://purl.uniprot.org/citations/24498420http://purl.uniprot.org/core/author"Rambaud J."xsd:string
http://purl.uniprot.org/citations/24498420http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/24498420http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/24498420http://purl.uniprot.org/core/name"PLoS ONE"xsd:string
http://purl.uniprot.org/citations/24498420http://purl.uniprot.org/core/name"PLoS ONE"xsd:string
http://purl.uniprot.org/citations/24498420http://purl.uniprot.org/core/pages"E87982"xsd:string
http://purl.uniprot.org/citations/24498420http://purl.uniprot.org/core/pages"E87982"xsd:string
http://purl.uniprot.org/citations/24498420http://purl.uniprot.org/core/title"JMJD6 regulates ERalpha methylation on arginine."xsd:string
http://purl.uniprot.org/citations/24498420http://purl.uniprot.org/core/title"JMJD6 regulates ERalpha methylation on arginine."xsd:string
http://purl.uniprot.org/citations/24498420http://purl.uniprot.org/core/volume"9"xsd:string
http://purl.uniprot.org/citations/24498420http://purl.uniprot.org/core/volume"9"xsd:string