http://purl.uniprot.org/citations/24813629 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/24813629 | http://www.w3.org/2000/01/rdf-schema#comment | "As a cleavage enzyme of precursor TNF-α, the high expression level of ADAM17 in endothelial cells is an important factor in atherosclerosis. In this study, we demonstrate that ADAM17 is the target of miR-152. We found that miR-152 could reduce TNF precursor cleavage and inhibit cell proliferation and migration by targeting ADAM17 in human umbilical vein endothelial cells (HUVECs). Furthermore, the expression pattern of miR-152 and corresponding target ADAM17 was opposite in HUVECs under hypoxic conditions. The levels of circulating miR-152 in AS patient sera were lower than those detected in the sera of normal individuals. Our results indicate that miR-152 may be involved in the development of human atherosclerosis and could be used as diagnostic biomarker or therapeutic target in atherosclerosis."xsd:string |
http://purl.uniprot.org/citations/24813629 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2014.04.037"xsd:string |
http://purl.uniprot.org/citations/24813629 | http://purl.uniprot.org/core/author | "Gao C."xsd:string |
http://purl.uniprot.org/citations/24813629 | http://purl.uniprot.org/core/author | "Hou L."xsd:string |
http://purl.uniprot.org/citations/24813629 | http://purl.uniprot.org/core/author | "Ge X."xsd:string |
http://purl.uniprot.org/citations/24813629 | http://purl.uniprot.org/core/author | "Li H."xsd:string |
http://purl.uniprot.org/citations/24813629 | http://purl.uniprot.org/core/author | "Li J."xsd:string |
http://purl.uniprot.org/citations/24813629 | http://purl.uniprot.org/core/author | "Li T."xsd:string |
http://purl.uniprot.org/citations/24813629 | http://purl.uniprot.org/core/author | "Huang A."xsd:string |
http://purl.uniprot.org/citations/24813629 | http://purl.uniprot.org/core/author | "Qin X."xsd:string |
http://purl.uniprot.org/citations/24813629 | http://purl.uniprot.org/core/author | "Wu Y."xsd:string |
http://purl.uniprot.org/citations/24813629 | http://purl.uniprot.org/core/author | "Zhao Q."xsd:string |
http://purl.uniprot.org/citations/24813629 | http://purl.uniprot.org/core/author | "Wang R."xsd:string |
http://purl.uniprot.org/citations/24813629 | http://purl.uniprot.org/core/author | "Su X."xsd:string |
http://purl.uniprot.org/citations/24813629 | http://purl.uniprot.org/core/author | "Ding H."xsd:string |
http://purl.uniprot.org/citations/24813629 | http://purl.uniprot.org/core/author | "Fang T."xsd:string |
http://purl.uniprot.org/citations/24813629 | http://purl.uniprot.org/core/author | "Shao N."xsd:string |
http://purl.uniprot.org/citations/24813629 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
http://purl.uniprot.org/citations/24813629 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
http://purl.uniprot.org/citations/24813629 | http://purl.uniprot.org/core/pages | "2063-2069"xsd:string |
http://purl.uniprot.org/citations/24813629 | http://purl.uniprot.org/core/title | "MiR-152 reduces human umbilical vein endothelial cell proliferation and migration by targeting ADAM17."xsd:string |
http://purl.uniprot.org/citations/24813629 | http://purl.uniprot.org/core/volume | "588"xsd:string |
http://purl.uniprot.org/citations/24813629 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/24813629 |
http://purl.uniprot.org/citations/24813629 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/24813629 |