| http://purl.uniprot.org/citations/25164943 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/25164943 | http://www.w3.org/2000/01/rdf-schema#comment | "Breast cancer is the most common malignancy in women worldwide. Environmental factors such as xenobiotic exposure and lifestyle and nutrition play a key role in its etiology. This study was designed to evaluate the age-related changes in the expression of major xenobiotic-metabolizing enzymes (XMEs) in the rat liver and the mammary gland in the dimethylbenz(a)anthracene-induced breast cancer model. The influence of dietary lipids on the ontogeny of XMEs was also evaluated. mRNA and protein levels of phase I (CYP1A1, CYP1A2, and CYP1B1) and phase II (NAD(P)H:quinone acceptor oxidoreductase 1 and GSTP1) enzymes were analyzed, as well as their regulation by AhR and Nrf2, respectively. Results showed differences in the phase I enzymes expression, whereas little changes were obtained in phase II. High corn oil and olive oil diets differentially influenced the expression of age-related changes, suggesting that the different susceptibility to xenobiotic exposure depending upon the age may be modulated by dietary factors."xsd:string |
| http://purl.uniprot.org/citations/25164943 | http://purl.org/dc/terms/identifier | "doi:10.1002/jbt.21596"xsd:string |
| http://purl.uniprot.org/citations/25164943 | http://purl.uniprot.org/core/author | "Vela E."xsd:string |
| http://purl.uniprot.org/citations/25164943 | http://purl.uniprot.org/core/author | "Escrich E."xsd:string |
| http://purl.uniprot.org/citations/25164943 | http://purl.uniprot.org/core/author | "Moral R."xsd:string |
| http://purl.uniprot.org/citations/25164943 | http://purl.uniprot.org/core/author | "Solanas M."xsd:string |
| http://purl.uniprot.org/citations/25164943 | http://purl.uniprot.org/core/author | "Escrich R."xsd:string |
| http://purl.uniprot.org/citations/25164943 | http://purl.uniprot.org/core/author | "Manzanares M.A."xsd:string |
| http://purl.uniprot.org/citations/25164943 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
| http://purl.uniprot.org/citations/25164943 | http://purl.uniprot.org/core/name | "J Biochem Mol Toxicol"xsd:string |
| http://purl.uniprot.org/citations/25164943 | http://purl.uniprot.org/core/pages | "539-548"xsd:string |
| http://purl.uniprot.org/citations/25164943 | http://purl.uniprot.org/core/title | "Ontogeny of the major xenobiotic-metabolizing enzymes expression and the dietary lipids modulatory effect in the rat dimethylbenz(a)anthracene-induced breast cancer model."xsd:string |
| http://purl.uniprot.org/citations/25164943 | http://purl.uniprot.org/core/volume | "28"xsd:string |
| http://purl.uniprot.org/citations/25164943 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/25164943 |
| http://purl.uniprot.org/citations/25164943 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/25164943 |
| http://purl.uniprot.org/uniprot/#_A6J4X2-mappedCitation-25164943 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25164943 |
| http://purl.uniprot.org/uniprot/#_A6IZ00-mappedCitation-25164943 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25164943 |
| http://purl.uniprot.org/uniprot/#_B6DYQ7-mappedCitation-25164943 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25164943 |
| http://purl.uniprot.org/uniprot/#_P04799-mappedCitation-25164943 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25164943 |
| http://purl.uniprot.org/uniprot/#_P04906-mappedCitation-25164943 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25164943 |
| http://purl.uniprot.org/uniprot/#_P05982-mappedCitation-25164943 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25164943 |
| http://purl.uniprot.org/uniprot/A6IZ00 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/25164943 |
| http://purl.uniprot.org/uniprot/P05982 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/25164943 |
| http://purl.uniprot.org/uniprot/P04906 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/25164943 |