RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/25451943http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/25451943http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/25451943http://www.w3.org/2000/01/rdf-schema#comment"A detailed understanding of the processes controlling adipogenesis is instrumental in the fight against the obesity epidemic. Adipogenesis is controlled by a transcriptional cascade composed of a large number of transcriptional factors, among which CCAAT/enhancer-binding protein (C/EBP) β plays an essential role. During 3T3-L1 adipocyte differentiation, C/EBPβ is induced early to transactivate the expression of C/EBPα and peroxisome proliferator-activated receptor γ (PPARγ), two master transcription factors for terminal adipocyte differentiation. Studies in recent years have revealed many new target genes of C/EBPβ, implicating its participation in many other processes during adipogenesis, such as mitotic clonal expansion, epigenetic regulation, unfolded protein response, and autophagy. Moreover, the function of C/EBPβ is highly regulated by post-translational modifications, which are crucial for the proper activation of the adipogenic program. Advances toward elucidation of the function and roles of the post-translational modification of C/EBPβ during adipogenesis will greatly improve our understanding of the molecular mechanisms governing adipogenesis."xsd:string
http://purl.uniprot.org/citations/25451943http://purl.org/dc/terms/identifier"doi:10.1074/jbc.r114.619957"xsd:string
http://purl.uniprot.org/citations/25451943http://purl.org/dc/terms/identifier"doi:10.1074/jbc.r114.619957"xsd:string
http://purl.uniprot.org/citations/25451943http://purl.uniprot.org/core/author"Guo L."xsd:string
http://purl.uniprot.org/citations/25451943http://purl.uniprot.org/core/author"Guo L."xsd:string
http://purl.uniprot.org/citations/25451943http://purl.uniprot.org/core/author"Li X."xsd:string
http://purl.uniprot.org/citations/25451943http://purl.uniprot.org/core/author"Li X."xsd:string
http://purl.uniprot.org/citations/25451943http://purl.uniprot.org/core/author"Tang Q."xsd:string
http://purl.uniprot.org/citations/25451943http://purl.uniprot.org/core/author"Tang Q."xsd:string
http://purl.uniprot.org/citations/25451943http://purl.uniprot.org/core/date"2015"xsd:gYear
http://purl.uniprot.org/citations/25451943http://purl.uniprot.org/core/date"2015"xsd:gYear
http://purl.uniprot.org/citations/25451943http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/25451943http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/25451943http://purl.uniprot.org/core/pages"755-761"xsd:string
http://purl.uniprot.org/citations/25451943http://purl.uniprot.org/core/pages"755-761"xsd:string
http://purl.uniprot.org/citations/25451943http://purl.uniprot.org/core/title"Transcriptional Regulation of Adipocyte Differentiation: A Central Role for CCAAT/Enhancer-binding Protein (C/EBP) beta."xsd:string
http://purl.uniprot.org/citations/25451943http://purl.uniprot.org/core/title"Transcriptional Regulation of Adipocyte Differentiation: A Central Role for CCAAT/Enhancer-binding Protein (C/EBP) beta."xsd:string
http://purl.uniprot.org/citations/25451943http://purl.uniprot.org/core/volume"290"xsd:string
http://purl.uniprot.org/citations/25451943http://purl.uniprot.org/core/volume"290"xsd:string
http://purl.uniprot.org/citations/25451943http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/25451943
http://purl.uniprot.org/citations/25451943http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/25451943
http://purl.uniprot.org/citations/25451943http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/25451943
http://purl.uniprot.org/citations/25451943http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/25451943